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Stimulants - Medication List
atomoxetine (Strattera ®) |
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Drug Category: Selective Norepinephrine Reuptake
Inhibitor. Indication: attention-deficit/hyperactivity disorder (ADHD). Dosing (usual): Treatment of ADHD in children and adolescents up to 70 kg body weight. Optimal doses appear to be 1.2 mg/kg daily, given once daily or in two divided doses. For children/adolescents over 70 kg body wt and adult patients, dose titration to 80 mg daily is recommended (single dose or two divided doses). Dosing (Adults): Treatment of ADHD: Oral: Initial: 40 mg/day, increased after minimum of 3 days to ~80 mg/day; may administer as either a single daily dose or 2 evenly divided doses in morning and late afternoon/early evening. May increase to 100 mg in 2-4 additional weeks to achieve optimal response. Dosage adjustment in patients receiving strong CYP2D6 inhibitors (eg, paroxetine, fluoxetine, quinidine): Do not exceed 80 mg/day; dose adjustments should occur only after 4 weeks. Note: Atomoxetine may be discontinued without the need for tapering dose. Supplied: Capsule: 10 mg, 18 mg, 25 mg, 40 mg, 60 mg, 80 mg, 100 mg |
benzphetamine (Didrex ®) |
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Initial: 25-50 mg po qd. Titrate to 25-50 mg po 1-3 times
daily. Max dose: 50 mg tid. [Supplied: 50 mg tablet] |
Caffeine (NoDoz ® , Vivarin ® ) |
| Dosing (Adults): 100-200 mg orally every 3 to 4 hours as needed |
dexmethylphenidate (Focalin ® ) |
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CNS stimulant. d-threo -enantiomer of racemic methylphenidate
hydrochloride. Indication: attention-deficit/hyperactivity disorder.
Focalin is administered twice daily, at least 4 hours apart. Patients new to methylphenidate: recommended starting dose for patients who are not currently taking methylphenidate, or for patients who are on stimulants other than methylphenidate: 5 mg/day (2.5 mg twice daily). Dosage may be adjusted in 2.5 to 5 mg increments to a maximum of 20 mg/day (10 mg twice daily). In general, dosage adjustments may proceed at approximately weekly intervals. Patients currently using methylphenidate: recommended starting dose is half the dose of methylphenidate. The maximum recommended dose is 20 mg/day (10 mg twice daily). |
Dextroamphetamine (Dexedrine ® ) |
| Narcolepsy/ADHD: 2.5 to 10 mg orally every morning or 2 to 3 times daily. Long acting: 10-15mg orally once daily. |
diethylpropion (Tenuate ® ) |
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Adult (usual) Obesity: controlled release: 75 mg orally daily.
Take mid-morning. Obesity: immediate release: 25 mg orally 3 times a
day, 1 hr before meals. May take 1 dose mid-evening, if desired, to
overcome night hunger. Supplied: 75 mg CR, 25 mg tablet. |
Methylphenidate (Concerta ®; Metadate ® ER; Metadate ® CD) |
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Other: Methylin ® ER; Methylin ®;
Ritalin-SR ®;
Ritalin ® LA;
Ritalin ® Dosing (Adults): Narcolepsy: Oral: 10 mg 2-3 times/day, up to 60 mg/day. Depression: Oral: Initial: 2.5 mg every morning before 9 AM; dosage may be increased by 2.5-5 mg every 2-3 days as tolerated to a maximum of 20 mg/day. May be divided (eg, 7 AM and 12 noon), but should not be given after noon. Do not use sustained release product. ADHD: Oral: Refer to pediatric dosing. Pediatric: ADHD: Oral: Children >/= 6 years: Initial: 0.3 mg/kg/dose or 2.5-5 mg/dose given before breakfast and lunch; increase by 0.1 mg/kg/dose or by 5-10 mg/day at weekly intervals; usual dose: 0.5-1 mg/kg/day; maximum dose: 2 mg/kg/day or 90 mg/day Extended release products: Metadate® ER, Methylin® ER, Ritalin® SR: Duration of action is 8 hours. May be given in place of regular tablets, once the daily dose is titrated using the regular tablets and the titrated 8-hour dosage corresponds to sustained release tablet size. Metadate® CD, Ritalin® LA: Initial: 20 mg once daily; may be adjusted in 10-20 mg increments at weekly intervals; maximum: 60 mg/day Concerta®: Initial dose: Children not currently taking methylphenidate: 18 mg once daily in the morning. Children currently taking methylphenidate: Note: Dosing based on current regimen and clinical judgment; suggested dosing listed below: Patients taking methylphenidate 5 mg 2-3 times/day or 20 mg/day sustained release formulation: 18 mg once every morning. Patients taking methylphenidate 10 mg 2-3 times/day or 40 mg/day sustained release formulation: 36 mg once every morning. Patients taking methylphenidate 15 mg 2-3 times/day or 60 mg/day sustained release formulation: 54 mg once every morning. Dose adjustment: May increase dose in increments of 18 mg; dose may be adjusted at weekly intervals. A dosage strength of 27 mg is available for situations in which a dosage between 18-36 mg is desired. Maximum dose should not exceed 2 mg/kg/day or 54 mg/day in children 6-12 years or 72 mg/day in children 13-17 years. Supplied: Capsule, extended release: Metadate® CD: 10 mg, 20 mg, 30 mg. Ritalin® LA: 10 mg, 20 mg, 30 mg, 40 mg. Solution, oral: Methylin®: 5 mg/5 mL (500 mL); 10 mg/5 mL (500 mL)] Tablet: 5 mg, 10 mg, 20 mg (Methylin®, Ritalin®: 5 mg, 10 mg, 20 mg) Tablet, chewable: Methylin®: 2.5 mg; 5 mg; 10 mg. Tablet, extended release: 20 mg. Concerta®: 18 mg, 27 mg, 36 mg, 54 mg [osmotic controlled release]. Metadate® ER, Methylin® ER: 10 mg, 20 mg. Tablet, sustained release (Ritalin-SR®): 20 mg |
Modafinil (Provigil ®) |
| Narcolepsy: Usual dose: 200mg orally once daily. [100, 200mg] |
Pemoline (Cylert ® ) |
| Adult (usual): Start 37.5 mg orally once daily in the morning. Usual effective dose: 56.25 to 75 mg/day. Max: 112.5 mg/day. Follow LFT's. |
phendimetrizine (Bontril SR ® , Prelu-2 ® ) |
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Adult (usual): Obesity: sustained release forms: 105 mg orally
once daily in the morning or before the morning meal. (Immediate release
forms): 35 mg orally 2-3 times daily. Maximum: 70 mg 3 times daily. In
some patients, one-half tablet (17.5 mg) was adequate. [Supplied: 105 mg SR, 35 mg tablet] |
phentermine (Fastin ® , Ionamin ®) |
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Adult (usual): 8 mg orally three times daily or 15 to 37.5 mg every morning.
Supplied: 8, 15, 18.75, 30. 37.5 mg |
sibutramine (Meridia ® ) |
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Anorexiant. Start -Obesity: 10 mg orally every morning. After
4 weeks may titrate up to 15 mg once daily as needed and tolerated (may
be used for up to 2 years). Max: 15 mg/day. [Supplied: 5, 10, 15 mg capsule] |
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any diagnosis or treatment made in reliance thereon. David F. McAuley, Pharm.D., R.Ph. GlobalRPh Inc. |
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