Rosuvastatin - Crestor® - Renal Dosing

Usual Dosing (Adults)
Usual initial dose: 10 mg once daily (range: 5 to 20 mg). Reserve higher initial dose for patients with severe hypercholesteremia or patients with homozygous familial hypercholesterolemia. May titrate dose after 2 weeks (increase by 5-10 mg once daily). Dosing range: 5-40 mg/day (maximum dose: 40 mg once daily).

Renal Dosing
dialysis [>30  mL/min/1.73 m2 ]: No changes.

[<30 mL/min/1.73 m2 - Not on hemodialysis]: Start at 5 mg qd. Do not exceed 10 mg qd.

Hemodialysis
dialysis Insufficient data. (Steady-state concentrations of rosuvastatin in patients on chronic hemodialysis were ~ 50% greater compared to healthy volunteer subjects with normal renal function).

Disclaimer
All calculations must be confirmed before use. The authors make no claims of the accuracy of the information contained herein; and these suggested doses are not a substitute for clinical judgement. Neither GlobalRPh Inc. nor any other party involved in the preparation of this program shall be liable for any special, consequential, or exemplary damages resulting in whole or part from any user's use of or reliance upon this material.PLEASE READ THE DISCLAIMER CAREFULLY BEFORE ACCESSING OR USING THIS SITE. BY ACCESSING OR USING THIS SITE, YOU AGREE TO BE BOUND BY THE TERMS AND CONDITIONS SET FORTH IN THE DISCLAIMER.   Read the disclaimer

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