Palm Pharmacokinetic dosing program for the health professional

Empiric dosing:

Step 1: Select empiric dosing (Click the title bar on the first screen to see the drop down program selector).

Step 2: (Select the drug and clearance method to be used). Click here for additional information regarding clearance calculations. When finished entering in all of the values, click the Next button at the top.

Step 3: After clicking Next on the first screen, you will arrive at this screen. Here you may select an alternative clearance method for vancomycin (if vanco was selected), or select a loading dose or amputation if present --->
Hit the Calculate regimen button to continue with the calculations

Sample of amputation correction factors found on the second screen.

Step 4 (Results screen): This is the screen that will appear after hitting Calculate regimen on the previous screen. Scan over these values then hit the Next button to modify the regimen. See step 5 for an editing example.

Step 5 (editing): Modify the regimen listed at the top (round values to a common interval and dosage). Simply place your pointer on the field you want to edit. Use graffiti strokes or the palm keyboard to edit these values. Below you will notice, that 157.2 was rounded to 160mg and 17.6 was rounded to 18 hours. When finished, press 'Compute final dose'. You will see the calculated predicted peak and trough at the bottom of the screen.

New screens (Updated 7/2003): Once daily dosing calculations have been re-introduced. Press the 'Once daily dosing calculations' button on the final calculation screen to pull up the second screen seen below. Next, select the drug and infection severity, then hit the 'Show' button to see calculated dose. You may then hit the 'Return' button at the top and enter these values into 'New dose' and 'New interval' fields.

Dosing by levels:

Step 1: select Dosing by levels

Step 2: simply tap on each entry point, and then use graffiti strokes or the palm keyboard to enter values. If you need help entering the values on this screen, see below for more info. When finished entering values, hit the Compute button.

Sample Problem to aid filling in the form: Patient is receiving Gentamicin 120mg IVPB q8h. Infusion time is 30 minutes. A peak of 6.0 is drawn 1 hour after the start of the infusion and a trough of 2.0 is drawn 5 hours after the start of the infusion. The program will take into account the infusion time when calculating the actual peak (do not subtract the infusion time from the number of hours post dose). This program assumes that information provided is based on steady state. If you were to calculate these values by hand, the actual Cmax would occur at the end of the infusion. In this example (t)= 1- 0.5 = 0.5. The Cmin calculation would use a time value of (8 - 5 = 3 hours).

Filling in the form (using example above):
Peak level Obtained:	6.0
Number hours post dose:	1.0
Trough Level Obtained:	2.0
Number of hours post dose:	5
Current dose:	120
Curr. Interval	8
Infusion time:	0.5