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Phenytoin Dosing Calculator

Patient Name:      Floor:
Age     Weight    Height
Gender      Current albumin level: (g/dl)
What is the current phenytoin level if available? (mcg/ml)
Dosage form used for maintenance dose:
Estimated creatinine clearance:
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     -    Program background information

Results

IBW (kg):    Dosing wt (kg):
Recommended loading dose for patient not currently receiving phenytoin:
10 mg/kg:  mg  15 mg/kg:  mg   20 mg/kg: mg
Recommended total daily maintenance dose (mg):
Range: ()  to  ()

Normally given in divided doses q8-12h. (Note: Use lower end of the range in patients with renal insufficiency or with low albumin levels)
Corrected level based on serum albumin:

(Correction based on the Sheiner-Tozer Method: Adjusted phenytoin concentration = Measured total concentration / [ (0.2 x albumin) + 0.1] )
Dose needed to increase level to therapeutic range if a sub-therapeutic level is entered above. (Dosages are based on a Vd of 0.7 L/kg. The corrected  level above is used as a starting point. Dosages below are in milligrams). 
Target 
12 mcg/ml: mg   15 mcg/ml: mg 17 mcg/ml: mg
 

Disclaimer

All calculations must be confirmed before use. The authors make no claims of the accuracy of the information contained herein; and these suggested doses are not a substitute for clinical judgement. Neither GlobalRPh Inc. nor any other party involved in the preparation of this program shall be liable for any special, consequential, or exemplary damages resulting in whole or part from any user's use of or reliance upon this material.PLEASE READ THE DISCLAIMER CAREFULLY BEFORE ACCESSING OR USING THIS SITE. BY ACCESSING OR USING THIS SITE, YOU AGREE TO BE BOUND BY THE TERMS AND CONDITIONS SET FORTH IN THE DISCLAIMER.   Read the disclaimer
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