GlobalRPh Inc
PKCalc  Pharmacokinetic dosing software for the Palm
(Internet download)
Try before you Buy!   Before purchasing, download a demo version to make sure the program meets your needs. The demo is a full version of the program that expires in 14 days.  Download (installer)
After testing the program on your PDA, use the link below to purchase the program:    BUY NOW for $24.95
Important:  After you purchase the program, you must register the program here to eliminate the demo mode. You must know your hotsync username to register.
Important notice: Our software is currently not compatible with the  new Palm OS 5.0 that is being released in the latest devices. Approximately 15-30% of the currently available palm applications will not be compatible with this new operating system. We predict that this problem should be resolved by the end of June 2003.  

System requirements:  Palm OS Version 3.0 or later. Compatible devices include Palm III, Palm IIIx, Palm IIIe, Palm IIIc, Palm V, Palm Vx, Palm VII, Palm m100; Handspring Visor; Symbol SPT 1500, 1700; TRG Pro; Sony CLIE (except OS 5.0).   
Empiric Dosing Dosing by levels
 

$24.95
Program Highlights:  (key features)
  • Two complete dosing calculators ('Empiric dosing' and 'Dosing by levels') with user adjustable result screens.
  • On-board levels and infusion time review screens for immediate reference.
  • Color enabled
  • Standalone executable (compiled in C code). Operating speed is increased by 2-3 times. (note: the registration system adds a slight delay at startup)
  • Does not require a runtime module. 
  • Contains an onboard keypad interface for fast, accurate entry.
  • Program is fully self-contained, not requiring external support programs such as Mathlib for complex mathematical functions.
  • Free lifetime product upgrades

System requirements:    (1)  Palm OS Version 3.0 or later. Compatible devices include Palm III, Palm IIIx, Palm IIIe, Palm IIIc, Palm V, Palm Vx, Palm VII, Palm m100; Handspring Visor; Symbol SPT 1500, 1700; TRG Pro; Sony CLIE.   (2) 140K for application
Program Operation
Empiric dosing:
Step 1:  Select empiric dosing Step 2:  (To access the drop-down menus, press on the small triangle as noted below.)  Select the drug.
Step 3: select once daily or conventional dosing. Step 4:  Use the on-screen keypad to enter values onto the screen. Simply tap 'Age' for example, then use the keypad to enter the value. Graffiti strokes are disabled on this screen. When you are finished with all of the fields, press [Enter/Calc]
Note: if you select once daily dosing, you must also select a dosing mode. If conventional dosing is selected, ignore this screen.

Step 5 (Results screen):  This is the screen you will see after you hit the 'enter' button. You can make adjustments to the infusion time, recommended dose, and interval. Here you would round these values to standard values. See step 6 for an editing example. Step 6 (editing):  Simply place your pointer on the field you want to edit. Below, is an example of editing the infusion time. Use graffiti strokes or the palm keyboard to edit these values. When finished, press 'Recalc'.  After pressing recalc, you will see Des. Peak and Des.trough change to 'New Peak' and New trough respectively.
   
Dosing by levels:
Step 1: select Dosing by levels Step 2: simply tap on each entry point, and then use the on-screen keyboard to enter values. If you need help entering the values on this screen, see below for more info. When finished entering values, hit the Enter button.
Sample Problem to aid filling in the form: Patient is receiving Gentamicin 120mg IVPB q8h. Infusion time is 30 minutes. A peak of 6.0 is drawn 1 hour after the start of the infusion and a trough of 2.0 is drawn 5 hours after the start of the infusion. The program will take into account the infusion time when calculating the actual peak (do not subtract the infusion time from the number of hours post dose). This program assumes that information provided is based on steady state. If you were to calculate these values by hand, the actual Cmax would occur at the end of the infusion. In this example (t)=  1- 0.5 = 0.5. The Cmin calculation would use a time value of (8 - 5 = 3 hours).
Filling in the form (using example above):
Peak level Obtained:   6.0
Number hours post dose: 1.0
Trough Level Obtained: 2.0
Number of hours post dose: 5
Current dose: 120
Curr. Interval 8
Infusion time: 0.5
 
Step 3:  After hitting enter you will see the screen below.  To edit the recommended dose, interval, or infusion time, simple place your pointer on the dashed line and use either graffiti strokes or the palm's built-in keypad to edit the values. When finished, hit the 'Recalc' button and you will see C-Peak and C-Trough values below change accordingly.
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Registering the PkCalc(After you have obtained the serial number from 
Step One:  Start the PkCalc program. You should then see the screen below.  
Step Two: tap the 'Pharmacokinetic Dosing' title at the top of the screen. You should then see the screen below.  Select Register from the drop-down list.
Step three: You should now see the screen below. Carefully enter the registration number you received from us, then hit the 'Enter' button. This will conclude the registration process.