Treatment of Influenza - Adults and Adolescents:
The recommended oral dose of TAMIFLU for treatment of influenza in adults and
adolescents 13 years and older is 75 mg twice daily for 5 days. Treatment should
begin within 2 days of onset of symptoms of influenza.
Prophylaxis of Influenza - Adults and Adolescents:
The recommended oral dose of TAMIFLU for prophylaxis of influenza in adults and
adolescents 13 years and older following close contact with an infected
individual is 75 mg once daily for at least 10 days. Therapy should begin within
2 days of exposure. The recommended dose for prophylaxis during a community
outbreak of influenza is 75 mg once daily. Safety and efficacy have been
demonstrated for up to 6 weeks in immunocompetent patients. Safety has been
demonstrated for up to 12 weeks in immunocompromised patients. The duration of
protection lasts for as long as dosing is continued.
Renal Dosing
Treatment of Influenza
Dose adjustment is recommended for adult patients with creatinine
clearance between 10 and 30 mL/min receiving
TAMIFLU for the treatment of influenza. In these patients it is
recommended that the dose be reduced to 75 mg of TAMIFLU once daily for
5 days. No recommended dosing regimens are available for patients with
end-stage renal disease undergoing routine hemodialysis or continuous
peritoneal dialysis treatment.
Prophylaxis of Influenza
For the prophylaxis of influenza, dose adjustment is recommended for
adult patients with creatinine clearance between 10 and 30 mL/min
receiving TAMIFLU. In these patients it is recommended that the dose be
reduced to 75 mg of TAMIFLU every other day or 30 mg TAMIFLU every day.
No recommended dosing regimens are available for patients undergoing
routine hemodialysis and continuous peritoneal dialysis treatment with
end-stage renal disease.
Hemodialysis
No recommended dosing regimens are available.
Disclaimer
The authors make no claims of the accuracy of the information contained herein; and these suggested doses are not a substitute for clinical
judgment. Neither GlobalRPh Inc. nor any other party involved in the
preparation of this program shall be liable for any special, consequential, or exemplary damages resulting in whole or part from any user's use of or reliance upon this material.PLEASE READ THE DISCLAIMER
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