Ophthalmic - Glaucoma Agents

Beta Blockers
Betaxolol (Betoptic ®)	Carteolol (Ocupress ®)
Levobunolol (Betagan ®)	Timolol (Timoptic ®)
Carbonic anhydrase inhibitors
Brinzolamide (Azopt ®)	Dorzolamide (Trusopt ®)
Cholinergics
Pilocarpine (Pilocar ®)
Prostaglandins
bimatoprost (Lumigan ®)	Latanoprost (Xalatan ®)
travoprost (Travatan ®)	unoprostone (Rescula ®)
Other
Apraclonidine (Iopidine ®)	Brimonidine (Alphagan ®)
Cosopt ® (dorzolamide 2% + timolol 0.5%)	Dipivefrin (Propine ®)

Beta Blockers

Betaxolol (Betoptic ®)

Dosing: 1-2 drops twice daily
Supplied: [0.25% susp , 0.5% soln]

Carteolol (Ocupress ®)

Dosing: 1 drop twice daily.
Supplied: [1% soln]

Levobunolol (Betagan ®)

Dosing: 1-2 drops once or twice daily.
Supplied: [0.25 & 0.5% soln]

Timolol (Timoptic ®)

Dosing: drop twice daily. Supplied: [soln 0.25 & 0.5%].
Timoptic XE: 1 drop once daily. Supplied: [0.25 & 0.5% gel]

Carbonic anhydrase inhibitors:

Brinzolamide (Azopt ®)

Dosing: 1 drop three times daily.
Supplied: [susp: 1%]

Dorzolamide (Trusopt ®)

Dosing: 1 drop three times daily
Supplied: [soln: 2%]

Cholinergics

Pilocarpine (Pilocar ®)

Indications: the treatment of primary open-angle glaucoma and also to lower intraocular pressure prior to surgery for acute angle-closure glaucoma. It may be used in combination with other miotics, beta adrenergic blocking agents, carbonic anhydrase inhibitors, hyperosmotic agents, or epinephrine.

Dosing: 1-2 drops 3 to 4 times daily or ½" gel at bedtime.
(The initial dose is one or two drops. This may be repeated up to six times daily. )

Prostaglandins

bimatoprost (Lumigan ®)

Dosing: Instill one drop in the affected eye(s) once daily in the evening. The dosage should not exceed once daily since it has been shown that more frequent administration may decrease the intraocular pressure lowering effect. [Supplied: 0.03% soln]

Latanoprost (Xalatan ®)

Dosing: 1 drop at bedtime.
Supplied: [soln: 0.005 %]

travoprost (Travatan ®)

Dosing: Instill one drop in the affected eye(s) once-daily in the evening. The dosage of TRAVATAN® should not exceed once-daily since it has been shown that more frequent administration may decrease the intraocular pressure lowering effect. [Supplied: 0.004% solution]

unoprostone (Rescula ®)

Dosing: Instill one drop in the affected eye(s) twice daily. RESCULA ® may be used concomitantly with other topical ophthalmic drug products to lower intraocular pressure. If two drugs are used, they should be administered at least five minutes apart. Structural analogue of an inactive biosynthetic cyclic derivative of arachidonic acid. [ Supplied: 0.15% solution ]

Other

Apraclonidine (Iopidine ®)

Dosing: 1-2 drops three times daily.
Supplied: [ soln: 0.5, 1%]

Brimonidine (Alphagan ®)

Dosing: 1 drop three times daily.
Supplied: [soln: 0.2%]

Cosopt ® (dorzolamide 2% + timolol 0.5%):

Dosing: 1 drop twice daily.

Dipivefrin (Propine ®)

Dosing: 1 drop twice daily.
Supplied: [soln: 0.1%]

Disclaimer

Listed dosages are for - Adult patients ONLY. PLEASE READ THE DISCLAIMER CAREFULLY BEFORE ACCESSING OR USING THIS SITE. BY ACCESSING OR USING THIS SITE, YOU AGREE TO BE BOUND BY THE TERMS AND CONDITIONS SET FORTH IN THE DISCLAIMER. GlobalRPH does not directly or indirectly practice medicine or provide medical services and therefore assumes no liability whatsoever of any kind for the information and data accessed through the Service or for any diagnosis or treatment made in reliance thereon.

David F. McAuley, Pharm.D., R.Ph. GlobalRPh Inc.