Ophthalmic Agents - Antibacterials and Combination Products

Ophthalmic agents - Home Page

Ciprofloxacin (Ciloxan ®) Erythromycin (Ilotycin ®) Gentamcyin (Garamycin ®) levofloxacin (Quixin ®) Neosporin ® (neomycin, bacitracin, polymixin ) norfloxacin (Chibroxin ®) Ofloxacin (Ocuflox ®) Polysporin ® (polymixinB-bacitracin) Polytrim (polymixin B - trimethoprim) Sulfacetamide (Bleph-10 ®, Sulamyd ®) Tobramycin (Tobrex ®)   Antibacterial & Corticosteroid Combinations Blephamide ® (sodium sufacetamide + prednisolone) Cortisporin ® (neomycin, polymixin, HC 1%) Maxitrol ® (dexamethasone + neomycin + polymixin) Pred G ® (gentamicin + prednisolone) TobraDex ® (Tobramycin + dexamethasone)

Ciprofloxacin (Ciloxan ®)

Adult (usual) Use 1 drop every 1 to 6 hours or ½" ointment 2 to 3 times daily. Supplied: [0.3% ointment, solution]

Erythromycin (Ilotycin ®)

Adult (usual): ½" of ointment every 3 to 4 hours or use 2 to 4 times daily. Supplied: [ointment 0.5%]

Gentamcyin (Garamycin ®)

Adult (usual): 1-2 drops every 4 hours or ½" ointment 2 to 3 times daily. Supplied: [0.3% oint/soln]

levofloxacin  (Quixin ®)

Adult (usual):  Dosing: Conjunctivitis: days 1-2, 1-2 drops every 2 hr while awake (Max 8 times/day); days 3-7, 1-2 drops every 4 hr while awake (Max 4 times/day) . [Supplied: 0.5% solution. ]

Neosporin ®  (neomycin, bacitracin, polymixin ):

Adult (usual): Dosing: 1-2 drops every 1 to 6 hours or ½" ointment every 3 to 4 hours.

norfloxacin (Chibroxin ®)

Adult (usual): Dosing -adults and pediatric patients(> 1 year old) conjunctivitis: 1 or 2 drops applied topically to the affected eye(s) 4 times daily for up to 7 days. Depending on the severity of the infection, the dosage for the first day of therapy may be one or two drops every two hours during the waking hours. Supplied: [0.3% soln].

Ofloxacin (Ocuflox ®)

Adult (usual):  Dosing: 1-2 drops every 1 to 6 hours depending on severity. Supplied: [0.3% soln]

Polysporin ® (polymixin B + bacitracin):

Adult (usual):  Ointment. Dosage and Administration: conjunctivitis: Apply the ointment every 3 or 4 hours for 7 to 10 days, depending on the severity of the infection.

Polytrim (polymixin B + trimethoprim):

Adult (usual):  Dosing: 1 drop every 3 to 6 hours. Maximum: 6 drops/day.

Sulfacetamide (Bleph-10 ®, Sulamyd ®)

Adult (usual):  Dosing: 1-2 drops every 2 to 6 hours or ½" ointment every 3 to 8 hours.

Tobramycin (Tobrex ®)

Adult (usual):  Dosing: 1-2 drops every 1 to 4 hours or ½" ointment every 3 to 4 hours or 2 to 4 times daily  Supplied: [0.3% oint/soln]

Antibacterial & Corticosteroid Combinations:

Blephamide ® (sodium sufacetamide + prednisolone):

Adult (usual): A steroid/anti-infective combination is indicated for steroid-responsive inflammatory ocular conditions for which a corticosteroid is indicated and where superficial bacterial ocular infection or a risk of bacterial ocular infection exists. SHAKE WELL BEFORE USING. (Solution): Two drops should be instilled into the conjunctival sac q4h during the day and at bedtime. (Ointment) Apply 1/2 inch ribbon of ointment in the conjunctival sac three or four times daily and once or twice at night. Not more than 8 g should be prescribed initially.

Cortisporin ® (neomycin, polymixin, HC 1%):

Adult (usual): Dosing: 1-2 drops or ½" ointment every 3 to 4 hours or more.

Maxitrol ® (dexamethasone + neomycin + polymixin):

Adult (usual):  Dosing: 1-2 drops every 1 to 8 hours or ½ to 1 inch ointment once or twice daily.

Pred G ® (gentamicin + prednisolone):

Adult (usual):  Suspension: Instill one drop into the conjunctival sac two to four times daily. During the initial 24 to 48 hours, the dosing frequency may be increased, if necessary, up to 1 drop every hour. Care should be taken not to discontinue therapy prematurely. If signs and symptoms fail to improve after two days, the patient should be re-evaluated. Supplied: PRED-G® (gentamicin 0.3% - prednisolone acetate 1.0% ophthalmic suspension) Ointment: A small amount ( 1 / 2 inch ribbon) of ointment should be applied in the conjunctival sac one to three times daily. Care should be taken not to discontinue therapy prematurely. Supplied:  PRED-G® (gentamicin 0.3% and prednisolone acetate 0.6% ophthalmic ointment)

TobraDex ® (Tobramycin + dexamethasone):

Adult (usual):  Dosing: 1-2 drops every 2 to 6 hours or ½" ointment 2 to 4 times daily.

Disclaimer

Listed dosages are for - Adult patients ONLY. PLEASE READ THE DISCLAIMER CAREFULLY BEFORE ACCESSING OR USING THIS SITE. BY ACCESSING OR USING THIS SITE, YOU AGREE TO BE BOUND BY THE TERMS AND CONDITIONS SET FORTH IN THE DISCLAIMER. GlobalRPH does not directly or indirectly practice medicine or provide medical services and therefore assumes no liability whatsoever of any kind for the information and data accessed through the Service or for any diagnosis or treatment made in reliance thereon. David F. McAuley, Pharm.D., R.Ph.  GlobalRPh Inc.