Ophthalmic Ocular Decongestants,  Anti-allergy Products

Ophthalmic agents - Home Page
azelastine (Optivar ®) Cromolyn sodium (Crolom ®)
emedastine (Emadine ®) Epinastine (Elestat ®)
Ketotifen Fumarate (Zaditor ®) Levocabastine (Livostin ®)
Lodoxamide tromethamine (Alomide ®) Naphazoline (Naphcon, Vasocon ®)
Naphcon-A ® (naphazoline + pheniramine) nedocromil (Alocril ®)
Olopatadine (Patanol ®) pemirolast (Alamast ®)

azelastine (Optivar ®)  top of page icon

Relatively selective H 1 -receptor antagonist for topical administration to the eyes. Indicated for the treatment of itching of the eye associated with allergic conjunctivitis. ADMINISTRATION: one drop instilled into each affected eye twice a day.

[Supplied: 0.05% ophthalmic solution]

Cromolyn sodium (Crolom ®) top of page icon

 Indications: Cromolyn sodium ophthalmic solution is indicated in the treatment of vernal keratoconjunctivitis, vernal conjunctivitis, and vernal keratitis.

Symptomatic response to therapy (decreased itching, tearing, redness and discharge) is usually evident within a few days, but longer treatment for up to six weeks is sometimes required. Once symptomatic improvement has been established, therapy should be continued for as long as needed to sustain improvement.

If required, corticosteroids may be used concomitantly with cromolyn sodium ophthalmic solution.
Users of soft (hydrophilic) contact lenses should refrain from wearing lenses while under treatment with cromolyn sodium ophthalmic solution. Wear can be resumed within a few hours after discontinuation of the drug.

Dosing:
The dose for adults and children is 1 or 2 drops in each eye 4 to 6 times a day at regular intervals. One drop contains approximately 1.6 mg cromolyn sodium.
Patients should be advised that the effect of cromolyn sodium ophthalmic solution therapy is dependent upon its administration at regular intervals, as directed.

Supplied:  CrolomTM (Cromolyn Sodium Ophthalmic Solution USP, 4%)

emedastine (Emadine ®) top of page icon

Emedastine is a selective H1-receptor antagonist with antiallergic and antiasthmatic properties.
 Dosing:  Allergic conjunctivitis: 1 drop 0.05% ophthalmic solution in affected EYE(s) up to four times daily.
 [Supplied: 0.05% solution] .

Epinastine  (Elestat ®)  top of page icon

H1 Blocker. Allergic conjunctivitis: Instill 1 drop into each eye twice daily. Continue throughout period of exposure, even in the absence of symptoms.

Supplied: Oph solution: 0.05% (5 ml).

Ketotifen Fumarate Ophthalmic Solution 0.025% (Zaditor ®) top of page icon

 Indications: Temporary prevention of itching of the eye caused by allergic conjunctivitis. Noncompetitive histamine antagonist (H-1 receptor) and mast cell stabilizer.

Dosing
The recommended dose is one drop in the affected eye(s) every 8 to 12 hours.

Supplied: Oph solution: 0.025% (5 ml).

Levocabastine (Livostin ®)  top of page icon

Indications: temporary relief of the signs and symptoms of seasonal allergic conjunctivitis.

Dosing
: The usual dose is one drop instilled in affected eyes four times per day.  SHAKE WELL BEFORE USING.

Supplied:
[suspension: 0.05%]

Lodoxamide tromethamine (Alomide ®)  top of page icon

Indications: treatment of the ocular disorders referred to by the terms vernal keratoconjunctivitis, vernal conjunctivitis, and vernal keratitis.

Dosing: The dose for adults and children greater than two years of age is one to two drops in each affected eye four times daily for up to 3 months.

Supplied: [soln: 0.1%]

Naphazoline (Naphcon, Vasocon ®)  top of page icon

Dosing: 1 drop every 3 to 4 hours as needed up to 4 times daily.

Naphcon-A ® (naphazoline + pheniramine): top of page icon

 Dosing: 1-2 drops 2 to 4 times daily as needed.

nedocromil (Alocril ®)  top of page icon

Mast cell stabilizer. Indication: allergic conjunctivitis.
Dosing: Instill one or two drops in each eye twice a day.

[Supplied: 2% ophthalmic soln]

Olopatadine (Patanol ®) top of page icon

Indications: treatment of the signs and symptoms of allergic conjunctivitis.

Dosing: The recommended dose is one drop in each affected eye two times per day at an interval of 6 to 8 hours.

Supplied: [0.1% soln]

pemirolast (Alamast ®)  top of page icon

Mast cell stabilizer. Indication: allergic conjunctivitis.
Dosing: Instill one to two drops in each affected eye four times daily. Symptomatic response to therapy (decreased itching) may be evident within a few days, but frequently requires longer treatment (up to four weeks).

Supplied: ophthalmic solution 0.1%
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Disclaimer

Listed dosages are for - Adult patients ONLY. PLEASE READ THE DISCLAIMER CAREFULLY BEFORE ACCESSING OR USING THIS SITE. BY ACCESSING OR USING THIS SITE, YOU AGREE TO BE BOUND BY THE TERMS AND CONDITIONS SET FORTH IN THE DISCLAIMER. GlobalRPH does not directly or indirectly practice medicine or provide medical services and therefore assumes no liability whatsoever of any kind for the information and data accessed through the Service or for any diagnosis or treatment made in reliance thereon.

David F. McAuley, Pharm.D., R.Ph.  GlobalRPh Inc.