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Oncology Intravenous Dilution Section

Alphabetical Listing   - Antineoplastic and Related Agents

[  A  ]

Adriamycin® (Doxorubicin HCL) Aldesleukin (Proleukin®) Alemtuzumab - Campath®
Alimta® (Pemetrexed) Amifostine - Ethyol® Arsenic Trioxide - Trisenox®
Asparaginase - Elspar® Avastin® (Bevacizumab) Azacitidine - Vidaza®

[  B  ]

BCG Live Vaccine - TheraCys®, TICE® BCG Bendamustine - Treanda® Bevacizumab - Avastin®
Bleomycin Bortezomib - Velcade®  

[  C  ]

Campath® (Alemtuzumab) Camptosar® (Irinotecan) Carboplatin - Paraplatin-AQ®
Carmustine - BiCNU® Cerubidine® (Daunorubicin HCL) Cetuximab - Erbitux®
Cisplatin -  Platinol-AQ® Cladribine - Leustatin® Cosmegen® (Dactinomycin)
Cyclophosphamide Cytarabine - Cytosar® Cytarabine (Liposomal)-DepoCyt®

[  D  ]

Dacarbazine Dactinomycin - Cosmegen® Daunorubicin HCL - Cerubidine®
Decitabine - Dacogen™ Denileukin Diftitox - ONTAK® Dexrazoxane - Totect®, Zinecard®
Dimethyl Sulfoxide - Rimso-50® Docetaxel - Taxotere® Dolasetron - Anzemet®
Doxorubicin HCL - Adriamycin® Doxorubicin (Liposomal)- Doxil®  

[  E - F - G  ]

Elitek™ (Rasburicase) Eloxatin® (Oxaliplatin) Elspar®
Epirubicin - Ellence® Erbitux® (Cetuximab) Ethyol®
Etoposide - Toposar® Floxuridine - FUDR® Fludarabine - Fludara®
Fluorouracil - Adrucil® , 5-FU Folotyn™ (Pralatrexate) Gemcitabine - Gemzar®
Gemtuzumab Ozogamicin-Mylotarg®    

[  H - I - J ]

Herceptin® (Trastuzumab) Hycamtin® (Topotecan) Ibritumomab - Zevalin®
Idarubicin - Idamycin PFS® Ifosfamide - Ifex® Irinotecan - Camptosar®
Ixabepilone - Ixempra™    

[  K - L - M ]

Leucovorin Calcium Leustatin® (Cladribine) Levoleucovorin - Fusilev™
Mechlorethamine - Mustargen® Melphalan - Alkeran® Mesna - Mesnex®
Methotrexate Mitomycin - Mutamycin® Mitoxantrone - Novantrone®

[  N - O - P - Q ]

Navelbine® (Vinorelbine) Nelarabine - Arranon® Ondansetron - Zofran®
Oxaliplatin - Eloxatin® Paclitaxel - Taxol® Paclitaxel (Protein Bound) - Abraxane®
Panitumumab - Vectibix® Pegaspargase - Oncaspar® Pemetrexed - Alimta®
Pentostatin - Nipent® Pralatrexate - Folotyn™ Proleukin® (Aldesleukin)

[  R - S - T ]

Rasburicase - Elitek™ Rituximab - Rituxan® Streptozocin - Zanosar®
Taxotere® (Docetaxel) Temsirolimus - Torisel™ Teniposide - Vumon®
Thiotepa Topotecan - Hycamtin® Trastuzumab - Herceptin®
Treanda® (Bendamustine) Trisenox® (Arsenic Trioxide)  

< U - V - WXYZ >

Vectibix® (Panitumumab) Velcade® (Bortezomib) Vidaza®
Vinblastine Vincristine - Vincasar PFS® Vinorelbine - Navelbine®
Vumon® (Teniposide) Zanosar® (Streptozocin) Zinecard® (Dexrazoxane)
Zoledronic acid - Zometa®    

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Extravasation Management

Chemotherapy vesicant & irritant properties and suggested management for extravasation

Always stop infusion of the causative medication first and, if appropriate, elevate the affected extremity. The venous access should not be removed immediately, since it can be used to attempt aspirating extravasated fluid and for administration of an antidote, if clinically appropriate. If an antidote is not going to be used, the venous access can be removed after aspiration of the extravasated fluid has been attempted. In general--aside from the exceptions listed below--keeping the extravasation cold is preferable to cause vasoconstriction, to prevent spread of the medication, and to decrease inflammation/pain. Some medications are more likely to have vesicant properties in high concentrations or large volumes. 
 [Source HemOnc.org  -See site for valuable guidance regarding individual agents as well as thousands of pages related to oncology. ]

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