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Burns Patients Awaiting Skin Grafts: Human Embryonic Stem-Cells Could Be Used To Generate Temporary Skin A study in this week's edition of The Lancet reports that the use of human embryonic stem-cells (hESCs) is a promising alternative for producing temporary skin substitutes for patients awaiting skin grafts after, for example, serious burn injuries. The article is the work of Dr Christine Baldeschi, INSERM and Institute for Stem Cell Therapy and Exploration of Monogenic Diseases, Evry Cedex, France, and colleagues. ...more	20 Nov 2009
Vitrolife Receives Research Grant From VINNOVA For Development Of The Clinical Stem-Cell Media Of Tomorrow VINNOVA announced in a press release yesterday that they are going to provide support of SEK 3.6 million for Vitrolife's research project for optimized culture media to enable the clinical use of stem cells. "It is very pleasing news and will enable more intensive work in an area that we very much believe in for the future", says Magnus Nilsson, Vitrolife's CEO. ...more	19 Nov 2009
Is Hepatic Differentiation Of Embryonic Stem Cells Induced By Valproic Acid And Cytokines? Embryonic stem (ES) cells, known for their capacity to proliferate indefinitely and differentiate into almost all types of cells including hepatocytes, have raised the hope of cellular replacement therapy for liver failure. There have been several protocols available for hepatic fate specification from ES cells, however, most of the protocols currently used result in low yield or purity of functional hepatocytes. ...more	19 Nov 2009
International Event At Queen's Focuses On Male Infertility Male infertility and tackling falling birth rates across Europe will be among the topics addressed at this year's British Andrology Society's annual conference at Queen's University in Belfast. World leaders in the field of andrology - the study of male reproduction - will meet at Queen's this week (Thursday and Friday) to discuss the latest developments in the field of fertility including the potential to create artificial sperm from stem cells. ...more	19 Nov 2009
NC State Researchers Advance Understanding Of Stem Cells Researchers from North Carolina State University have identified a gene that tells embryonic stem cells in the brain when to stop producing nerve cells called neurons. The research is a significant advance in understanding the development of the nervous system, which is essential to addressing conditions such as Parkinson's disease, Alzheimer's disease and other neurological disorders. ...more	19 Nov 2009
Transplanting People's Own Stem Cells Into Heart Lessens Pain, Improves Ability To Walk The largest national stem cell study for heart disease showed the first evidence that transplanting a potent form of adult stem cells into the heart muscle of subjects with severe angina results in less pain and an improved ability to walk. The transplant subjects also experienced fewer deaths than those who didn't receive stem cells. ...more	19 Nov 2009
Cancer-Fighting Drugs Delivered Right To The Tumor An encapsulation breakthrough by researchers at the Technion-Israel Institute of Technology may enable doctors to deliver anti-cancer drugs directly to tumors over extended periods of time, while preventing the systemic side effects of chemotherapy and other current cancer treatments. The system consists of polymeric microcapsules containing human mesenchymal stem cells (MSCs) engineered to produce proteins that prevent cancer growth. ...more	18 Nov 2009
Recent Developments At Burnham Institute For Medical Research, November 2009 New antibiotics for methicillin-resistant Staphylococcus aureus (MRSA) and other pesky bacteria. Andrei Osterman and collaborators have used comparisons of bacterial genomes to identify new targets for antibiotics and produced first-generation chemical inhibitors of a class of bacterial enzymes, called NadDs (nicotinate mononucleotide adenylyltransferases). Described in a recent article in Chemistry & Biology (Cell Press), the team, led by Dr. ...more	18 Nov 2009
Stem Cells Improve Heart Function In Patients With Cardiomyopathy A Florida cardiologist is using stem cell therapy to treat patients who suffer from a range of heart, lung and vascular illnesses. The results have been extraordinary. Zannos Grekos, M.D. uses the patients' own stem cells to treat the diseases. "One's own stem cells offer great potential for the treatment of serious heart, lung and vascular diseases," Dr. Grekos said. "We are seeing remarkable outcomes through this treatment. ...more	18 Nov 2009
BrainStorm Stem Cell Therapy Technology Possesses Promising Potential For The Future Treatment Of Multiple Sclerosis BrainStorm Cell Therapeutics Inc. (OTCBB:BCLI), a leading developer of adult stem cell technologies and therapeutics, is pleased to announce that the company's therapeutic approach for treating neurodegenerative diseases, particularly ALS and Parkinson's disease, was found to have a positive effect in a mouse model of multiple sclerosis (MS). ...more	18 Nov 2009
The Indefinite Self Renewal Of Specialized Cells Without The Need For Stem Cell Intermediates Is the indefinite expansion of adult cells possible without recourse to stem cell intermediates? The team led by Michael Sieweke at the Centre d'immunologie de Marseille Luminy (UniversitÃ© Aix-Marseille 2 / CNRS / INSERM) has proved that this is the case by achieving the ex vivo regeneration for several months of macrophages, specialized cells in the immune system. Published in Science on November 6, 2009, this discovery could be applied to other cell types. ...more	17 Nov 2009
Partners United In Saving Lives - Canadian Blood Services From November 14th through 21st, Canadian Blood Services' stem cell program, the OneMatch Stem Cell and Marrow Network, is marking National Stem Cell Awareness Week with its Partners Uniting Lives campaign. Sadly, only 30 per cent of patients in need of a stem cell transplant will find a match within their own family - the rest turn to OneMatch. ...more	16 Nov 2009
Finding May Give Hope To More Leukemia Patients So They May Live Cancer-Free A new study from the Masonic Cancer Center, University of Minnesota shows that patients who have acute leukemia and are transplanted with two units of umbilical cord blood (UCB) have significantly reduced risk of the disease returning. This finding has the potential to change the current medical practice of using one unit of UCB for treatment of patients who are at high risk for recurrence of leukemia and other cancers of the blood and bone marrow. Michael Verneris, M.D. ...more	16 Nov 2009
Pioneering Discoveries About The Development Of Cells How does the developing pancreas in an embryo 'know' which cells are to produce insulin and which cells are to have other assignments? Researchers need to understand this if they want to be able to treat type-1 diabetes with stem cells developed into insulin-producing beta cells. At Lund University scientists have uncovered pioneering new knowledge, and are publishing it in the journal Cell. ...more	14 Nov 2009
The Use Of Stem Cells In Regenerative Medicine May Be Detrimental For Health The use of stem cells in regenerative medicine is not always beneficial for human health, it may even be harmful according to a work done by the University of Granada and University of LeÃ³n. Scientists have demonstrated that transplantation of human mononuclear cells isolated from umbilical cord blood exerted a deleterious effect in rats with liver cirrhosis. ...more	14 Nov 2009
For MRI Tracking Of Stem Cells, $1M In Stimulus Funds Awarded To Rice, Texas Heart Institute The National Institutes of Health (NIH) has awarded researchers at Rice University and the Texas Heart® Institute (THI) a $1 million Challenge Grant to refine cell-tracking nanotube technology that could make magnetic resonance imaging (MRI) up to 40 times more sensitive than existing MRIs and help guide adult stem cells within the human body to repair damaged hearts. ...more	12 Nov 2009
OncoVista (OVIT) AdnaGen Test Identifies Cancer Stem Cells In The Bloodstream OncoVista Innovative Therapies, Inc. (Pink Sheets:OVIT) reported today that two of its proprietary products, the AdnaTest™ BreastCancer and AdnaTest EMT1/StemCell, were evaluated in Germany by the Departments of Gynecology and Obstetrics and Internal Medicine (Cancer Research) at University Hospital Essen, University of Duisburg-Essen and the Department of Gynecology and Obstetrics, University Hospital of Tuebingen. ...more	12 Nov 2009
To Heal Diabetic Foot Ulcers, A New Drug Harnesses Stem Cells Inside Us All Diabetic foot ulcers are the primary cause of hospital admissions for diabetics. Foot ulcers that heal improperly are at risk for infection, which can lead to amputation. According to the American Diabetes Association, one in four patients with diabetic foot ulcers will eventually require lower-limb amputation. Now science has found a way of mobilizing stem cells within the body to treat this health issue, which affects more than three million Americans annually. ...more	11 Nov 2009
BrainStorm Stem Cell Therapy Treatment Shown To Be More Effective Than Other Current Potential Stem Cell Treatments BrainStorm Cell Therapeutics Inc. (OTCBB:BCLI), a leading developer of adult stem cell technologies and therapeutics, is pleased to announce that the company's therapeutic approach for treating neurodegenerative diseases was shown to be superior to other current potential stem cell treatments. ...more	11 Nov 2009
$11 Million NIH Grant For Stem Cell Research Awarded To Rhode Island Hospital Rhode Island Hospital has received an $11 million grant to fund research that will lead to a general understanding of stem cell biology and identify unique approaches to tissue regeneration in lung and marrow diseases. The 5-year grant, awarded to Peter Quesenberry, MD, director of hematology/oncology at Rhode Island Hospital, also provides funding for the development of a major stem cell research center at Rhode Island Hospital. ...more	10 Nov 2009
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