Can EP4 Agonist Alleviate Gastric Lesions?
Over 300 million patients use non-steroidal anti-inflammatory drugs (NSAIDs) in the world to treat pain, arthritis, fever and other diseases. Nearly 30% of the users suffer from gastric lesions and bleeding. To mitigate NSAIDs' adverse effects on the stomach, misoprostol, a non-selective prostaglandin E1 (PGE1) analogue, has been prescribed as the first choice for prevention of NSAID-induced injuries, but often induces severe adverse effects. ...more
19 Nov 2009
CNSBio Inc. To Present Latest Clinical Trial Data For CNSB015 At Neuropathic Pain Conference In San Francisco
CNSBio Inc. will present recent Phase IIa proof-of-concept clinical trial data for CNSB015, an orally administered potassium channel modulator used in combination with opioids for the treatment of neuropathic pain, at the 12th International Conference on the Mechanisms and Treatment of Neuropathic Pain on November 20-21, 2009 in San Francisco, CA. Dr. ...more
19 Nov 2009
Common Pain Relief Medication May Encourage Cancer Growth
Although morphine has been the gold-standard treatment for postoperative and chronic cancer pain for two centuries, a growing body of evidence is showing that opiate-based painkillers can stimulate the growth and spread of cancer cells. Two new studies advance that argument and demonstrate how shielding lung cancer cells from opiates reduces cell proliferation, invasion and migration in both cell-culture and mouse models. ...more
19 Nov 2009
Transplanting People's Own Stem Cells Into Heart Lessens Pain, Improves Ability To Walk
The largest national stem cell study for heart disease showed the first evidence that transplanting a potent form of adult stem cells into the heart muscle of subjects with severe angina results in less pain and an improved ability to walk. The transplant subjects also experienced fewer deaths than those who didn't receive stem cells. ...more
19 Nov 2009
Explanation For Rapid Maturation Of Neurons At Birth Found By Duke Researchers
At the moment a newborn switches from amniotic fluid to breathing air, another profound shift occurs: nerve cells in the brain convert from hyperexcitability to a calm frame against which outside signals can be detected. "Fetal neurons need hyperexcitability for proper development, because they are moving to the right places (in the brain) and forming the right connections," said Wolfgang Liedtke, M.D., Ph.D. ...more
18 Nov 2009
FDA Approves New Drug Treatment For Long-Term Pain Relief After Shingles Attacks
The Food and Drug Administration (FDA) has approved the approval of Qutenza (capsaicin) 8% patch, a medicated skin patch that relieves the pain of post-herpetic neuralgia (PHN), a serious complication that can occur after a bout with shingles. Shingles is an outbreak of rash or blisters on the skin that is caused by the same virus that causes chickenpox - the varicella-zoster virus. ...more
18 Nov 2009
Acetaminophen-Related Liver Damage May Be Prevented By Common Herbal Medicine
A well-known Eastern medicine supplement may help avoid the most common cause of liver transplantation, according to a study by researchers at the Stanford University School of Medicine. The finding came as a surprise to the scientists, who used a number of advanced genetic and genomic techniques in mice to identify a molecular pathway that counters acetaminophen toxicity, which leads to liver failure. ...more
Need For Emergency Airway Surgery For Hard-to-Intubate Patients Reduced
Be prepared, that old Boy Scout motto, is being applied with great success to operating room patients whose anatomy may make it difficult for physicians to help them breathe during surgery, Johns Hopkins researchers report in a new study. When patients undergo general anesthesia, they stop breathing on their own and anesthesiologists must quickly insert a tube into the airway as a first step in machine-assisted breathing. ...more
18 Nov 2009
Five Exercises Reduce Neck Pain Of Women Office Workers
Strength training exercises using dumbbells can reduce pain and improve function in the trapezius muscle, the large muscle which extends from the back of the head, down the neck and into the upper back. The exercises also improve the muscle's ability to respond quickly and forcefully among women suffering trapezius myalgia, a tenderness and tightness in the upper trapezius muscle. ...more
18 Nov 2009
What Is Dystonia? What Causes Dystonia?
Dystonia is a general term which describes involuntary movements and extended muscle contractions - a range of movement disorders. The patient has twisting body movements, tremor and unusual or awkward postures. For some patients the whole body may be involved in the movements, while for others only certain parts of the body are affected. Dystonia symptoms may be linked to specific tasks, such as writing, as in writer's cramp. ...more
18 Nov 2009
Recovering With 4-Legged Friends Requires Less Pain Medication
Adults who use pet therapy while recovering from total joint-replacement surgery require 50 percent less pain medication than those who do not. These findings were presented at the 18th Annual Conference of the International Society of Anthrozoology and the First Human Animal Interaction Conference (HAI) in Kansas City, Mo. ...more
18 Nov 2009
Winston Laboratories, Inc. Announces Positive Top-line Results Of Phase II Clinical Trial Of Civamide Patch
Winston Laboratories, Inc. ("Winston Labs"), a wholly-owned subsidiary of Winston Pharmaceuticals, Inc. (OTC BB: WPHM) today announced positive top-line results from Study WL1001-04-03, a Phase II clinical trial evaluating the safety and efficacy of the company's patch formulation of Civamide, a novel TRPV-1 receptor modulator in the treatment of post-herpetic neuralgia (PHN). The study successfully demonstrated the efficacy of Civamide Patch 0. ...more
18 Nov 2009
FDA Discusses Neuromed NDA Application For Exalgo
Covidien (NYSE: COV) announced that on November 13, 2009, representatives of Neuromed discussed the pending New Drug Application (NDA) for the product candidate ExalgoTM (hydromorphone HCl extended release) tablets with staff from the United States Food and Drug Administration (FDA). Mallinckrodt Inc., a Covidien company, obtained the commercial rights to Exalgo in the United States from Neuromed Development Inc., a subsidiary of Neuromed Pharmaceuticals Ltd., in June 2009. ...more
18 Nov 2009
Need To Address Hemophilia In Developing World Highlighted By Research
When modern medicine finds a way to treat a medical condition, people often think that the problem is solved. But we also have to find ways to get that treatment into the hands of those who need it. For example, new research from North Carolina State University shows that much more needs to be done to help get existing treatment to hemophilia patients in the developing world, and that the current lack of treatment there is costing lives. ...more
17 Nov 2009
BioElectronics Technology More Effective Than Extra Strength Tylenol(R) In Reducing Muscle Soreness In Clinical Study
BioElectronics Corp. (PINKSHEETS: BIEL) announced that its disposable drug-free anti-inflammatory devices proved to be significantly more effective than acetaminophen in a clinical study of Delayed Onset Muscle Soreness (DOMS). The study tested the effectiveness of ActiPatch® Therapy versus acetaminophen in reducing the pain of Delayed Onset Muscle Soreness, a condition associated with increased physical exertion. ...more
17 Nov 2009
Recovering With Four-Legged Friends Requires Less Pain Medication
Adults who use pet therapy while recovering from total joint-replacement surgery require 50 percent less pain medication than those who do not. These findings were presented at the 18th Annual Conference of the International Society of Anthrozoology and the First Human Animal Interaction Conference (HAI) in Kansas City, Mo. ...more
17 Nov 2009
Depression Patients More Apt To Receive Opioids For Chronic Pain
Chronic pain patients with a history of depression are three times more likely to receive long-term prescriptions for opioid medications like Vicodin compared to pain patients who do not suffer from depression, according to new research. The study, published in the November-December issue of the journal General Hospital Psychiatry, analyzed the medical records of tens of thousands of patients enrolled in the Kaiser Permanente and Group Health plans between 1997 and 2005. ...more
16 Nov 2009
Can Thinking Of A Loved One Reduce Your Pain?
"The very thought of you … the mere idea of you" - from the song "The Very Thought of You" by Ray Noble Can the mere thought of your loved one reduce your pain? Yes, according to a new study by UCLA psychologists that underscores the importance of social relationships and staying socially connected. ...more