GlobalRPH - Huntingtons Disease News

Medical News

< back to feeds
Huntingtons Disease News
Researchers Find Potential Treatment For Huntington's Disease Investigators at Burnham Institute for Medical Research (Burnham), the University of British Columbia's Centre for Molecular Medicine and Therapeutics and the University of California, San Diego have found that normal synaptic activity in nerve cells (the electrical activity in the brain that allows nerve cells to communicate with one another) protects the brain from the misfolded proteins associated with Huntington's disease. ...more	16 Nov 2009
Better Understanding Of Synaptic Activity May Support 'Use It Or Lose It' Hypothesis In Huntington's Disease Investigators at Burnham Institute for Medical Research (Burnham), the University of British Columbia's Centre for Molecular Medicine and Therapeutics and the University of California, San Diego have found that normal synaptic activity in nerve cells (the electrical activity in the brain that allows nerve cells to communicate with one another) protects the brain from the misfolded proteins associated with Huntington's disease. ...more	16 Nov 2009
Efficacy Of Gene Therapy In Mouse Models Of Huntington's Disease Shown By Caltech Researchers Researchers at the California Institute of Technology (Caltech) have shown that a highly specific intrabody (an antibody fragment that works against a target inside a cell) is capable of stalling the development of Huntington's disease in a variety of mouse models. "Gene therapy in these models successfully attenuated the symptoms of Huntington's disease and increased life span," notes Paul Patterson, the Anne P. and Benjamin F. Biaggini Professor of Biological Sciences. ...more	02 Nov 2009
New TAU Formulation May Slow Down Parkinson's, Alzheimer's And Huntington's Diseases Working like an architect, Prof. Hagit Eldar-Finkelman of Tel Aviv University's Sackler School of Medicine is "building" a new drug, L803-MTS, to treat a number of central nervous system (CNS) diseases like Alzheimer's. In pre-clinical studies, it also shows promise against Parkinson's, Huntington's and diabetes. L803-MTS is based on the physical structure of the GSK3 protein, which plays a causative role in insulin resistance and Type II diabetes. ...more	28 Oct 2009
Gladstone And Partners Receive $3.7 Million For Huntington's Disease Research The National Institutes of Health (NIH) has awarded a "Grand Opportunity" grant of $3.7 million to a consortium formed with the Gladstone Institute of Neurological Disease (GIND) and the Taube-Koret Center for Huntington's Disease Research to use stem cell technology to better understand Huntington's disease (HD) and to develop potential therapies. ...more	15 Oct 2009
Protein Inhibitor Helps Rid Brain Of Toxic Tau Protein Inhibiting the protein Hsp70 rapidly reduces brain levels of tau, a protein associated with Alzheimer's disease when it builds up abnormally inside nerve cells affecting memory, neuroscientists at the University of South Florida found. The study is reported online today in the Journal of Neuroscience. ...more	30 Sept 2009
Mechanism For Potential Friedreich's Ataxia Drug Uncovered Using clever chemistry, a Scripps Research team has pinpointed the enzyme target of a drug group that stops the progression of the devastating disease Friedreich's ataxia in mice and may do the same for humans. The findings, developed in collaboration with scientists from Repligen Corporation, help advance this treatment approach one step closer toward human clinical trials, which will be a welcome event for disease sufferers who currently have few treatment options. ...more	28 Sept 2009
What Is Huntington's Disease? What Causes Huntington's Disease? Huntington's disease is an incurable, hereditary brain disorder. It is a devastating brain disorder for which there is no currently 'effective' treatment. Nerve cells become damaged, causing various parts of the brain to deteriorate. The disease affects movement, behavior and cognition - the affected individuals' abilities to walk, think, reason and talk are gradually eroded to such a point that they eventually become entirely reliant on other people for their care. ...more	02 Aug 2009
Pfizer And Medivation Initiate Phase 3 Trial Of Dimebon In Patients With Huntington Disease Pfizer Inc (NYSE: PFE) and Medivation, Inc. (NASDAQ: MDVN) announced the initiation of a Phase 3 trial of the investigational drug dimebon (latrepirdine) in patients with Huntington disease. The international safety and efficacy trial, known as HORIZON, is designed to evaluate the potential benefits of dimebon on cognition (thinking and memory) in patients with Huntington disease. The companies also announced that the U.S. ...more	01 Aug 2009
Disturbed Calcium Signaling May Play A Critical Role In Brain Cell Degeneration University of Utah School of Medicine researchers and their colleagues at University of Texas (UT) Southwestern Medical Center have found strong evidence that abnormal calcium signaling in neurons may play an important role in the development of spinocerebellar ataxia type 2 (SCA2), a disorder causing progressive loss of coordination, speech difficulty, and abnormal eye movements. Their findings are published in the July 27, 2009 issue of Journal of Neuroscience. ...more	23 July 2009
In Huntington's Patients, Transplanted Neurons Develop Disease-Like Pathology The results of a recent study published in PNAS question the long-term effects of transplanted cells in the brains of patients suffering from Huntington's disease. This study, conducted jointly by Dr. Francesca Cicchetti of UniversitÃ© Laval in Quebec, Canada, Dr. Thomas B. ...more	21 July 2009
Huntington's: Researchers Gain Insight Into Mechanism Underlying The Disease Researchers at the University of Kentucky Markey Cancer Center and Graduate Center for Toxicology (GCT) have gained new insight into the genetic mechanisms underlying Huntington's disease and other neurodegenerative or neuromuscular disorders caused by trinucleotide repeats (or TNRs) in DNA. The research, performed in the laboratory of Dr. ...more	15 July 2009
Huntington's Disease Deciphered Researchers at the University of Illinois at Chicago College of Medicine have discovered how the mutated huntingtin gene acts on the nervous system to create the devastation of Huntington's disease. The report of their findings is available in Nature Neuroscience online. ...more	15 June 2009
Risk Of Discrimination For Individuals With Family History Of Genetic Disease A research published on bmj.com reports that individuals with a family history of genetic disease are frequently discriminated by their relatives, friends and also by insurance companies. Many individuals have been able to adapt treatment and inform reproductive decisions thanks to the developments in genetic testing. ...more	12 June 2009
Transmission Of Huntington's Disease To Offspring Among Male Carriers: Risk Estimated By Researchers Researchers from Boston University School of Medicine (BUSM) have quantified the probability of a male who carries a "high normal" variant of the Huntington's Disease (HD) gene having a child who develops the disease. Although thought to be a very rare event, the probability has never been estimated using current information and disease guidelines. The findings, appear on-line in the American Journal of Medical Genetics, may be useful during prenatal genetic counseling. ...more	11 June 2009
Discovery Of Tiny Protein-Activator Responsible For Brain Cell Damage In Huntington Disease Johns Hopkins brain scientists have figured out why a faulty protein accumulates in cells everywhere in the bodies of people with Huntington's disease (HD), but only kills cells in the part of the brain that controls movement, causing negligible damage to tissues elsewhere. The answer, reported this week in Science, lies in one tiny protein called "Rhes" that's found only in the part of the brain that controls movement. ...more	06 June 2009
Identifying Pathways In The Brain To Understand The Underlying Molecular Mechanism Of Huntington's Disease Florida Atlantic University researcher Dr. Jianning Wei, assistant professor of biomedical sciences in the Charles E. Schmidt College of Biomedical Science at FAU, has received a grant from the National Institutes of Health (NIH) to further her research into the molecular mechanisms of Huntington's disease (HD). Named after American physician George Huntington, HD is a highly complex genetic, neurological disorder that causes certain nerve cells in the brain to waste away. ...more	21 May 2009
New Tool Helps Researchers Identify DNA Patterns Of Cancer, Genetic Disorders A new tool will help researchers identify the minute changes in DNA patterns that lead to cancer, Huntington's disease and a host of other genetic disorders. The tool was developed at North Carolina State University and translates DNA sequences into graphic images, which allows researchers to distinguish genetic patterns more quickly and efficiently than was historically possible using computers. David Cox, a Ph.D. ...more	20 May 2009
Gene Key To Alzheimer's-Like Reversal In Mice Identified By MIT-Led Team A team led by researchers at MIT's Picower Institute for Learning and Memory has now pinpointed the exact gene responsible for a 2007 breakthrough in which mice with symptoms of Alzheimer's disease regained long-term memories and the ability to learn. ...more	07 May 2009
Small Molecules Might Block Mutant Protein Production In Huntington's Disease Molecules that selectively interfere with protein production can stop human cells from making the abnormal molecules that cause Huntington's disease, researchers at UT Southwestern Medical Center have found. These man-made molecules also were effective against the abnormal protein that causes Machado-Joseph disease, a neurological condition similar to Huntington's. ...more	04 May 2009
Pages of Results: 1 2 3 4 5 6 7 8 [Next] [Last Page]
Huntingtons Disease News courtesy of Medical News Today	back to top

Medical News

Looking for a Job?

Career Center

Popular Tools

Disclaimer Contact Us Privacy Policy Website Search	We comply with the HONcode standard for health trustworthy information: Verify here. Copyright © 2007 GlobalRPh Inc.