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New Certified Reference Materials Offer Greater Certainty In Monitoring 3 Therapeutic Medications To help bring greater certainty to the measurement of medication levels in a patient's bloodstream for three drugs with narrow therapeutic ranges, the U.S. Pharmacopeial Convention (USP) is releasing new certified reference materials (CRMs). ...more	20 Nov 2009
Increased Risk Of Seizures Faced By Current Cigarette Smokers A recent study determined there is a significant risk of seizure for individuals who currently smoke cigarettes. Boston-based researchers from Brigham and Women's Hospital and Harvard Medical School also found that long-term, moderate intake of caffeine or alcohol does not increase the chance of having a seizure or developing epilepsy. ...more	19 Nov 2009
University Of Montreal Study Reveals Danger To Fetus Of Certain Drugs More than six percent of expectant mothers in Quebec consume prescription drugs that are known to be harmful to their fetuses, according to a UniversitÃ© de MontrÃ©al investigation published in the British Journal of Obstetrics and Gynaecology. Half these women will voluntarily terminate their pregnancy fearing congenital malformations, which means the abortion rate among these women is 11 percent higher than in the rest of the population. ...more	18 Nov 2009
Explanation For Rapid Maturation Of Neurons At Birth Found By Duke Researchers At the moment a newborn switches from amniotic fluid to breathing air, another profound shift occurs: nerve cells in the brain convert from hyperexcitability to a calm frame against which outside signals can be detected. "Fetal neurons need hyperexcitability for proper development, because they are moving to the right places (in the brain) and forming the right connections," said Wolfgang Liedtke, M.D., Ph.D. ...more	18 Nov 2009
New Study Challenges Established Ideas About Long And Short Term Memory Researchers in the UK are challenging the long-established idea that our brains use different mechanisms for making long and short term memories: they suggest that while some mechanisms are separate, other mechanisms are shared. ...more	11 Nov 2009
NeuroTherapeutics Pharma Receives Investment From The Epilepsy Therapy Project NeuroTherapeutics Pharma, Inc., or NTP, a biopharmaceutical company focused on developing novel therapies for central nervous system (CNS) disorders, today announced that it received a $100,000 investment from the Epilepsy Therapy Project. The Epilepsy Therapy Project invests in promising research efforts in order to help make new therapies a reality for patients, and the investment in NTP is one of the largest made in its history. ...more	11 Nov 2009
Ikano Therapeutics Receives Orphan Drug Designation For Epilepsy Drug Ikano Therapeutics, Inc. (ITI) announced that it has received Orphan Drug designation for midazolam in the acute treatment of certain forms of epileptic seizure known as cluster seizures or alternatively, as acute repetitive seizures. ITI has a nasally administered form of midazolam called ITI-111 in late stage clinical development that is aimed at the treatment of these specific seizure types in an outpatient setting where other routes of administration can be difficult or inappropriate. ...more	11 Nov 2009
Alzheimer's Society Comment On The Use Of Epilepsy Drugs To Treat Alzheimer's Epilepsy drugs could be developed as a treatment for neurodegenerative diseases according to research published in the journal Molecular Neurodegeneration. The study found that nerve cells lived longer when treated with T-type calcium-channel blockers, which are commonly used to treat epilepsy. 'This study is interesting since other research has shown that anti-convulsant drugs reduce the tangles of proteins linked to Alzheimer's disease. ...more	29 Oct 2009
Alzheimer's And Parkinson's Could Be Treated By Epilepsy Drugs Researchers in the USA have discovered a potential new function for anti-epileptic drugs in treating neurodegenerative disorders such as Alzheimer's and Parkinson's disease. The study, published in BioMed Central's open access journal Molecular Neurodegeneration, found that neurons in the brain were protected after treatment with T-type calcium-channel blockers, which are commonly used to treat epilepsy. ...more	29 Oct 2009
Epilepsy Treatment Is A Possible Culprit For Development Of Schizophrenia Researchers say antiepilectic drug treatments administered when the brain is developing appear to trigger schizophrenia-like behavior in animal models. In humans, having a history of seizures in infancy is a significant risk factor for development of schizophrenia later in life, but it is not known whether the elevated risk is due to seizures themselves, or from side effects antiepileptic drug (AED) treatment. ...more	21 Oct 2009
Improved Understanding Of Why Seizures Occur With Alcohol Withdrawal Epileptic seizures are the most dramatic and prominent aspect of the "alcohol withdrawal syndrome" that occurs when a person abruptly stops a long-term or chronic drinking habit. Researchers have shown that the flow of calcium ions into brain cells via voltage-gated calcium channels plays an important role in the generation of alcohol withdrawal seizures, because blocking this flow suppresses these seizures. ...more	19 Oct 2009
'Molecular Trigger' For Sudden Death In Epilepsy Revealed By BCM Scientists The most common gene for a syndrome associated with abnormal heart rhythms and sudden death triggers epileptic seizures and could explain sudden unexplained death in epilepsy, said researchers from Baylor College of Medicine in a report that appears today in the journal Science Translational Medicine. ...more	15 Oct 2009
How A Well-Known Epilepsy And Pain Drug Works A Duke University Medical Center researcher who spent years looking for the signals that prompt the brain to form new connections between neurons has found one that may explain precisely how a well-known drug for epilepsy and pain actually works. The finding may also point to new therapies for brain injury and neuropathic pain. The role of neurons in the brain and nervous system is well known, but astrocytes, a different type of brain cell, still are largely a mystery. ...more	15 Oct 2009
Registry To Track Children With Infantile Spasms Researchers have launched an online registry that ultimately aims to help children with a severe type of epilepsy that strikes in the first months of life. It is believed to be the first worldwide registry of children with infantile spasms and is a collaboration between Washington University School of Medicine in St. Louis and the University of Chicago. ...more	10 Oct 2009
Study Pinpoints Key Mechanism In Brain Development, Raising Question About Use Of Antiseizure Drug Researchers at the Stanford University School of Medicine have identified a key molecular player in guiding the formation of synapses - the all-important connections between nerve cells - in the brain. This discovery, based on experiments in cell culture and in mice, could advance scientists' understanding of how young children's brains develop as well as point to new approaches toward countering brain disorders in adults. ...more	09 Oct 2009
U.S. Lags Behind Industrialized Countries On Preventable Deaths The United States lags behind other wealthy countries on "preventable deaths," those caused by illnesses and injuries that should not kill at an early age, and it has been falling further behind over the past decade. The Washington Post reports: "Although the United States now spends $2. ...more	07 Oct 2009
Routine Stroke Prevention Therapies Are Underused In The Very Elderly But Could Be Very Effective; And More Research In Epilepsy In Very Old Needed Routine stroke prevention therapies are underused in the very elderly, but could be very effective in this age group. The issues are discussed in a Review published Online First and in the November edition of The Lancet Neurology, written by Dr Nerses Sanossian and Dr Bruce Ovbiagele, University of Southern California, Los Angeles, CA, USA. As the average human lifespan increases there are more individuals above the age of 80 years who have a high quality of life. ...more	07 Oct 2009
Very Elderly Age Group: Need For Routine Stroke Prevention Therapies And Research In Epilepsy A review published Online First and in the November edition of The Lancet Neurology reports that routine stroke prevention therapies are underused in the very elderly, but could be very effective in this age group. The article is the work of Dr Nerses Sanossian and Dr Bruce Ovbiagele, of the University of Southern California, Los Angeles, CA, USA. ...more	05 Oct 2009
Researchers Question The Use Of Antiepileptic Drugs During Pregnancy New research to be published in BJOG: An International Journal of Obstetrics and Gynaecology reports the pregnancy complications experienced by women with epilepsy and examines the use of antiepileptic drugs (AED) for treatment during pregnancy. Epileptic women (around 0.3-0.7% of the population) who become pregnant are classified as high-risk because prolonged fits can be dangerous for the baby as well as the mother. ...more	30 Sept 2009
Certain Colours More Likely To Cause Epileptic Fits Researchers have discovered that epileptic brains are more ordered than non-epileptic ones and also that certain flicking colours seem more likely to cause fits. In 1997, more than seven hundred children in Japan suffered an epileptic attack while watching an episode of Pokemon cartoon. ...more	26 Sept 2009
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