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New Certified Reference Materials Offer Greater Certainty In Monitoring 3 Therapeutic Medications To help bring greater certainty to the measurement of medication levels in a patient's bloodstream for three drugs with narrow therapeutic ranges, the U.S. Pharmacopeial Convention (USP) is releasing new certified reference materials (CRMs). ...more	20 Nov 2009
Mood Dysfunction Improved In Gene Knockout Mice Removing the PKCI/HINT1 gene from mice has an anti-depressant-like and anxiolytic-like effect. Researchers writing in the open access journal BMC Neuroscience applied a battery of behavioral tests to the PKCI/HINT1 knockout animals, concluding that the deleted gene may have an important role in mood regulation. ...more	14 Nov 2009
Faulty Body Clock May Make Kids Bipolar Malfunctioning circadian clock genes may be responsible for bipolar disorder in children. Researchers writing in the open access journal BMC Psychiatry found four versions of the regulatory gene RORB that were associated with pediatric bipolar disorder. ...more	12 Nov 2009
Mental Health America Applauds Bipartisan Legislation To Help Treat Depression And Bipolar Disorders Mental Health America is applauding legislation introduced by a bipartisan group of U.S. Senators to establish national centers of excellence for the treatment of depression and bipolar disorders. The centers will create a national network to help diagnose people in need and improve access to evidence-based, quality care. The bill, called the "ENHANCED Act" was introduced by U.S. Senators Debbie Stabenow (D-Mich. ...more	29 Oct 2009
Break-through Preventative Care Program For People Living With Bipolar Disorder A major breakthrough in mental health has been developed, a cooperative venture between the National Bipolar Foundation and the MedicAlert Foundation; a preventative care program called "Safe 'til Stable." It provides vital medical information to emergency responders in time of need through our live 24-hour emergency response service. In a medical emergency, this can help reduce the trauma experienced by individuals impacted with bipolar disorder. ...more	28 Oct 2009
Funding Supports ADA Technologies' Development Of Home Monitor For Bipolar Disorder ADA Technologies, Inc. (ADA) received a $189,886 grant from the National Institute of Mental Health to develop a home lithiummonitor for use by patients with bipolar disorder. The testing tool would allow reliable, routine at-home monitoring of blood lithium concentrations, enabling individuals with bipolar disorder to conveniently and effectively manage their care. Effective treatment of bipolar disorder, an inherited disease that affects 5. ...more	28 Oct 2009
UNC Study Pinpoints Gene Controlling Number Of Brain Cells The finding suggests that a single gene, called GSK-3, controls the signals that determine how many neurons actually end up composing the brain. This has important implications for patients with neuropsychiatric illness, as links have recently been drawn between GSK-3 and schizophrenia, depression and bipolar disorder. ...more	06 Oct 2009
Young Adults May Outgrow Bipolar Disorder Bipolar disorder, or manic-depression, causes severe and unusual shifts in mood and energy, affecting a person's ability to perform everyday tasks. With symptoms often starting in early adulthood, bipolar disorder has been thought of traditionally as a lifelong disorder. Now, University of Missouri researchers have found evidence that nearly half of those diagnosed between the ages of 18 and 25 may outgrow the disorder by the time they reach 30. ...more	30 Sept 2009
Yale Researchers Succeed In Repairing Brain Damage Caused By Chronic Stress, Lead Poisoning, Potential Implications For Bipolar Disorder Yale University researchers report in the Proceedings of the National Academy of Sciences (September 7-11 edition) that damage to the brain caused by chronic stress or lead poisoning can be repaired by blocking a key molecular pathway. Research shows that rats exposed to chronic stress develop damage to the prefrontal cortex. This is an area of the brain essential to working memory, impulse control and the ability to stay focused on tasks. ...more	10 Sept 2009
Yale Researchers Repair Brain Damage Caused By Chronic Stress Work Has Implications For Bipolar Disorder, PTSD Damage to the brain caused by chronic stress or lead poisoning can be repaired by blocking a key molecular pathway, Yale University researchers report in the September 7-11 edition of the Proceedings of the National Academy of Sciences. Rats subjected to chronic stress develop damage to the prefrontal cortex, an area of the brain crucial to working memory, impulse control and the ability to stay focused on tasks. ...more	09 Sept 2009
AstraZeneca Traveling Exhibit Helps Americans Understand And Manage Bipolar Depression As part of its ongoing effort to support bipolar depression awareness and education, AstraZeneca (NYSE: AZN) is bringing The Bipolar Journey: Living With Bipolar Depression interactive exhibit to patients and caregivers across America. Those who have been touched by bipolar depression -- the depressive phase of bipolar disorder -- are encouraged to visit a nearby exhibit site and learn more about living with this disease and how to help manage it. ...more	28 Aug 2009
FDA Approves Saphris Tablets (asenapine) To Treat Schizophrenia And Bipolar Disorder The U.S. Food and Drug Administration has approved Saphris tablets (asenapine) to treat adults with schizophrenia, a chronic, severe and disabling brain disorder, and to treat bipolar I disorder in adults, a serious psychiatric disorder that causes shifts in a person's mood, energy, and ability to function. "Mental illnesses like schizophrenia and bipolar disorder can be devastating to patients and families, requiring lifelong treatment and therapy," said Thomas Laughren, M.D. ...more	16 Aug 2009
Schering-Plough Announces FDA Approval Of SAPHRIS(R) (asenapine) For Acute Treatment Of Schizophrenia In Adults And Manic Or Mixed Episodes Of Bipolar Schering-Plough Corporation (NYSE: SGP) announced that the U.S. Food and Drug Administration (FDA) has approved SAPHRIS((R)) (asenapine) sublingual tablets for acute treatment of schizophrenia in adults and acute treatment of manic or mixed episodes associated with bipolar I disorder with or without psychotic features in adults. SAPHRIS can be used as a first-line treatment and is the first psychotropic drug to receive initial approval for both of these indications simultaneously. ...more	15 Aug 2009
Mental Illness Was The Costliest Condition Between 1996 To 2006 The number of Americans under care for depression and other mental illnesses nearly doubled between 1996 and 2006, and the overall cost of treating them jumped by nearly two-thirds, according to the latest News and Numbers from HHS' Agency for Healthcare Research and Quality. According to the analysis by the federal agency, the number of patients treated for mental disorders, including depression and bipolar disease, increased from 19 million to 36 million. ...more	06 Aug 2009
Mental Illness Was One Of The Costliest Conditions Between 1996 To 2006 The number of Americans under care for depression and other mental illnesses nearly doubled between 1996 and 2006, and the overall cost of treating them jumped by nearly two-thirds, according to the latest News and Numbers from HHS' Agency for Healthcare Research and Quality. According to the analysis by the federal agency, the number of patients treated for mental disorders, including depression and bipolar disease, increased from 19 million to 36 million. ...more	06 Aug 2009
What Rorschach Tests Really Tell Us One of the most well-known psychological tools is the Rorschach Inkblot Test. A viewer looks at ten inkblots, one at a time, and describes what they see. The rationale behind this test is the idea that certain aspects of the subject's personality will be exposed as they are interpreting the images, allowing for the possible diagnosis of various psychological disorders. ...more	31 July 2009
FDA Advisory Committee Votes In Favor Of SAPHRIS(R) (asenapine) For Acute Bipolar I Disorder And Acute Schizophrenia Schering-Plough Corporation (NYSE: SGP) announced that the U.S. Food and Drug Administration (FDA) Psychopharmacologic Drugs Advisory Committee voted unanimously in favor of SAPHRIS(R) (asenapine) sublingual tablets as effective and safe for the acute treatment of manic or mixed episodes associated with bipolar I disorder in adults and in favor of use in acute treatment of schizophrenia in adults. ...more	31 July 2009
If Bipolar Disorder Is Over-Diagnosed, What Are The Actual Diagnoses? A year ago, a study by Rhode Island Hospital and Brown University researchers reported that fewer than half the patients previously diagnosed with bipolar disorder received an actual diagnosis of bipolar disorder after using a comprehensive, psychiatric diagnostic interview tool -- the Structured Clinical Interview for DSM-IV (SCID). In this follow-up study, the researchers have determined the actual diagnoses of those patients. ...more	30 July 2009
Patients With Bipolar Disorder At Increased Risk For Wide Range Of Health Problems, Thomson Reuters Study Finds A new study from Thomson Reuters found that patients with bipolar disorder were at greater risk for a wide range of medical conditions than a control group of patients with no mental health diagnoses. The study analyzed de-identified insurance claims for more than 600,000 Americans with employer-sponsored insurance. It is available here and an interactive graphic charting bipolar patients' risk of comorbid disorders is available here. ...more	29 July 2009
Stanford To Offer Bipolar Education Day On July 25 The Stanford University School of Medicine will host its fifth annual Bipolar Education Day on July 25. Individuals with bipolar disorder, their families, caregivers, friends and interested community members are invited to attend. The free event will be held at the William R. Hewlett Teaching Center at 370 Serra St., located on the main campus. More than 5. ...more	08 July 2009
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