Codeine

4–6 h

3 h

IM

120 mg

PO

200 mg

Fentanyl

1–2 h

1.5–6 h

IM

0.1 mg

Hydrocodone

4–8 h

3.3–4.5 h

PO

30 mg

Hydromorphone

4–5 h

2–3 h

IM

1.3–1.5 mg

PO

7.5 mg

Levorphanol

6–8 h

12–16 h

IM

2 mg

PO

4 mg

Meperidine

2–4 h

3–4 h

IM

75 mg

PO

300 mg

Methadone

4–6 h

15–30 h

IM

10 mg

PO

10–20 mg

Morphine

3–7 h

1.5–2 h

IM

10 mg

PO

30–60 mg

Oxycodone

4–6 h

NA

PO

15-30 mg (20 mg)

Oxymorphone

3–6 h

NA

IM

1 mg

PR

10 mg

Propoxyphene

4–6 h

6–12 h

PO

130-200 mg *
(Inconclusive data)

*Propoxyphene HCL: 130mg;  Napsylate: 200mg. Not recommended for chronic pain.