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Magnesium Dosing
This document Copyright © 2005  D.McAuley, GlobalRPh Inc. All Rights Reserved.

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All calculations must be confirmed before use. This Service is intended to be used for informational purposes only and is not intended to be used for medical diagnosis or treatment or to substitute for a medical diagnosis and/or treatment rendered or prescribed by a physician or competent healthcare professional. GlobalRPH does not directly or indirectly practice medicine or provide medical services and therefore assumes no liability whatsoever of any kind for the information and data accessed through the Service or for any diagnosis or treatment made in reliance thereon. 
References:
(1)  Flink EB. Magnesium deficiency. Etiology and clinical spectrum.  Acta Med Scand Suppl 1981;647:125-37

"The documentation of normal renal function is absolutely necessary for maximum doses. The order of magnitude of dose is 1.0 meq Mg/kg on day 1, and 0.3 to 0.5 mEq/kg per day for 3 to 5 days. In emergencies such as convulsions or ventricular arrhythmias, a bolus injection of 1.0 gm (8.1 meq) of MgSO4 is indicated. Therapy of Mg deficiency in the presence of renal insufficiency requires smaller doses and frequent monitoring. Complete repletion occurs slowly."

(2) Abbott LG, Rude RK.  Department of Endocrinology, LAC+USC Medical Center, Los Angeles 90033.  Clinical manifestations of magnesium deficiency. Miner Electrolyte Metab 1993;19(4-5):314-22.


(3) Berkelhammer C, Bear RA.  A clinical approach to common electrolyte problems: 4. Hypomagnesemia.  Can Med Assoc J 1985 Feb 15;132(4):360-8. 


(4) DiPalma JR. Magnesium replacement therapy.  Am Fam Physician 1990 Jul;42(1):173-6


(5) al-Ghamdi SM, Cameron EC, Sutton RA. Magnesium deficiency: pathophysiologic and clinical overview. Am J Kidney Dis. 1995 Jun;25(6):973.  // 
Am J Kidney Dis 1994 Nov;24(5):737-52. 


(6)  Tso EL, Barish RA.  Magnesium: clinical considerations.  J Emerg Med 1992 Nov-Dec; 10(6):735-45. 


(7)  Kingston ME, Al-Siba'i MB, Skooge WC.  Clinical manifestations of hypomagnesemia. 
Crit Care Med 1986 Nov;14(11):950-4 . 


(8)  Whang R, Hampton EM, Whang DD.  Magnesium homeostasis and clinical disorders of magnesium deficiency.  Ann Pharmacother 1994 Feb;28(2):220-6.

 

 
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