Lorazepam
Ativan ® |
| Usual
Diluents |
| D5W,
NS |
| Standard
Dilutions [Amount of drug]
[Infusion volume] [Infusion rate] |
Dilute 2 mg/ml (10 ml vials) or 4 mg/ml (10 ml) vials 1:1 with D5W or NS. May add to viaflex bag.
Alternatively: Glass bottle: 40 mg/250 ml (250ml D5W). Infusion Rate: As directed. (See comments).
Primary:
Dilution for 2 mg/ml - 10 ml vials.
= Final Concentration 1 mg/ml ==
20 mg/20 ml (10 ml diluent + 10ml of drug) Total volume =20ml.
40 mg/ 40 ml (20 ml diluent + 20ml of drug) Total volume =40ml.
80 mg/ 80 ml (40 ml diluent + 40ml of drug) Total volume =80ml.
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| Stability
/ Miscellaneous |
EXP: 1 DAY (RT)
Label: Do not Refrigerate /An in-line 0.22u filter should be used.
Concentrations recommended by the manufacturer: 0.1 , 0.16, or 0.2 mg/ml.
May also dilute 4 mg/ml and 2 mg/ml vials 1:1 with D5W or NS.
Do not send if solution is yellow or contains a precipitate.
Maximum infusion rate: 2 mg/min.
Maximum dose/day: 480 mg (20 mg/hr).
Dosing: Status epilepticus: 4 mg IV push (range: 2 to 8 mg).
May repeat q5 to 15 minutes.
Monitor patient for acidosis. |
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