Lorazepam  Ativan ®

Usual Diluents

D5W,   NS

Standard Dilutions   [Amount of drug]  [Infusion volume]  [Infusion rate]

Dilute 2 mg/ml (10 ml vials) or 4 mg/ml (10 ml) vials 1:1 with D5W or NS. May add to viaflex bag. Alternatively: Glass bottle: 40 mg/250 ml (250ml D5W). Infusion Rate: As directed. (See comments). Primary: Dilution for 2 mg/ml - 10 ml vials. = Final Concentration 1 mg/ml  == 20 mg/20 ml  (10 ml diluent + 10ml of drug) Total volume =20ml. 40 mg/ 40 ml  (20 ml diluent + 20ml of drug) Total volume =40ml. 80 mg/ 80 ml  (40 ml diluent + 40ml of drug) Total volume =80ml.

Stability / Miscellaneous

EXP: 1 DAY (RT)  Label: Do not Refrigerate /An in-line 0.22u filter should be used.  Concentrations recommended by the manufacturer: 0.1 , 0.16, or 0.2 mg/ml.  May also dilute 4 mg/ml and 2 mg/ml vials 1:1 with D5W or NS.  Do not send if solution is yellow or contains a precipitate.  Maximum infusion rate: 2 mg/min.  Maximum dose/day: 480 mg (20 mg/hr).  Dosing: Status epilepticus: 4 mg IV push (range: 2 to 8 mg).  May repeat q5 to 15 minutes.  Monitor patient for acidosis.