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Levetiracetam
Keppra ®
Usual
Dosing (Adults)
Partial onset seizures (adjunctive):
Initially, 500 mg po bid. May increase q2weeks by 500 mg/dose to a max of 1500 mg
bid.
Renal
Dosing
[CRCL
>80 ml/min]: 500-1500 mg q12h
[50 - 80]: 500-1000 mg q12h
[30 - 50]: 250-750 mg q12h
[<30 ml/min]: 250-500 mg q12h
Hemodialysis
500-1000 mg
q24h. Supplemental dose of 250 to 500 mg following dialysis is recommended.
