Partial onset seizures (adjunctive): Initially, 500 mg po bid. May increase
q2weeks by 500 mg/dose to a max of 1500 mg bid.
Renal Dosing
[CRCL >80 ml/min]: 500-1500 mg q12h
[50 - 80]: 500-1000 mg q12h
[30 - 50]: 250-750 mg q12h
[<30 ml/min]: 250-500 mg q12h
Hemodialysis
500-1000 mg q24h. Supplemental dose of 250 to 500 mg following
dialysis is recommended.
Disclaimer
All calculations must be confirmed before use. The authors make no claims of the accuracy of the information contained herein; and these suggested doses are not a substitute for clinical
judgement. Neither GlobalRPh Inc. nor any other party involved in the
preparation of this program shall be liable for any special, consequential, or exemplary damages resulting in whole or part from any user's use of or reliance upon this material.PLEASE READ THE DISCLAIMER
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