Lansoprazole  Prevacid IV ®

Usual Diluents

NS, LR, D5W

Standard Dilutions   [Amount of drug]  [Infusion volume]  [Infusion rate]

[30 mg] [50 ml] [30 min] ------------------------------ Unlabeled Use: GI Bleed Bolus dose: [60 mg] [100 ml] [60 min] Continuous infusion: [60 mg] [100 ml] [10ml/hr]    = 6 mg/hr.

Stability / Miscellaneous

IMPORTANT: See Package insert for instructions for Priming the finished admiture and using the provided filter. Stability: 24 hours (room temperature):  if diluted with NS or LR.  12 hour stability if diluted with D5W. Label: Do not refrigerate. // IN-LINE FILTER MUST BE USED. Reconstitution in Vial and Preparation of Admixture: There are two steps for preparing Prevacid I.V. for Injection. STEP ONE - Reconstitution in Vial - First Prevacid I.V. MUST be reconstituted with Sterile Water for Injection, USP. - Inject 5 mL of ONLY Sterile Water for Injection, USP into a 30 mg vial of PREVACID I.V. for Injection. The resulting solution will contain lansoprazole 6 mg/mL (30 mg/5 mL). - Failure to reconstitute with Sterile Water may result in formation of precipitation/particulates. - Mix gently until the powder is dissolved. The pH of this reconstituted solution is approximately 11. The reconstituted solution can be held for 1 hour when stored at room temperature prior to further dilution. STEP TWO - Preparation of Admixture - Dilute the reconstituted solution in either 50 mL of 0.9% Sodium Chloride Injection, USP, Lactated Ringer’s Injection, USP, or 5% Dextrose Injection, USP.