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Itraconazole
Sporanox ®
Usual
Dosing (Adults)
Oral: 100-400mg po qd or divided doses - bid. (Doses >200 mg/day are given in 2 divided doses.)
IV: 200 mg IV q12h x 4 doses, then 200mg qd.
Renal
Dosing
Intravenous itraconazole should not be used in patients with creatinine clearance <30 ml/min.
Oral dosage form: no adjustment necessary.
Hemodialysis
Intravenous itraconazole should not be used in patients with creatinine clearance <30 ml/min.