Ibutilide Corvert ®

Usual Diluents

D5W,  NS

Standard Dilutions   [Amount of drug]  [Infusion volume]  [Infusion rate]

[0 to 1 mg] [50 ml] [10 min]

Stability / Miscellaneous

EXP: 1 DAY (RT) / 2 DAYS (REF). May be administered undiluted as well.  Indications: rapid conversion of A-fib/flutter of recent onset.  Dosing:  patient wt >60kg: 1 mg over 10min.  If < 60kg: 0.01 mg/kg over 10 min.  If the arrhythmia does not terminate within 10 minutes after the 1st dose, a 2nd dose may be given 10 minutes after the completion of the first infusion.  Mechanism of action : prolongs action potential duration and increases both atrial & ventricular refractoriness (class III agent).