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Medications which may induce hyperglycemia



 
Agents/medications linked to hyperglycemia
Aminophylline Amprenavir
Alpha-interferon Asparaginase
Beta-agonists Caffeine
Chlorpromazine Calcitonin
Corticosteroids Cyclophosphamide
Diltiazem Diazoxide
Didanosine Estrogens
Ethacrynic acid Furosemide
Haloperidol Indinavir
Indomethacin Isoniazid
Levodopa Lithium
Morphine Methyldopa
megestrol acetate Nelfinavir
Nicotine Oral contraceptives
Phenothiazines Phenytoin
Pentamidine Ritonavir
Saquinavir Sympathomimetics
Theophylline Thiazides
Thyroxine Vacor
References:

1. Assan R, Perronne C, Assan D, Chotard L, Mayaud C, Matheron S, Zucman D: Pentamidine-induced derangements of glucose homeostasis. Diabetes Care 18:4755, 1995 

2. Bouchard P, Sai P, Reach G, Caubarrere I, Ganeval D, Assan R: Diabetes mellitus following pentamidine-induced hypoglycemia in humans. Diabetes 31:4045, 1982 

3.  Fabris P, Betterle C, Floreani A, Greggio NA, de Lazzari F, Naccarato R, Chiaramonte M: Development of type 1 diabetes mellitus during interferon alpha therapy for chronic HCV hepatitis. Lancet 340:548, 1992 

4.  Gallanosa AG, Spyker DA, Curnow RT: Diabetes mellitus associated with autonomic and peripheral neuropathy after Vacor poisoning: a review. Clin Toxicol 18:441449, 1981 

5.  O'Byrne S, Feely J: Effects of drugs on glucose tolerance in non-insulin-dependent diabetes (parts I and II). Drugs 40:203219, 1990 

6.  Package Inserts.

7.  Pandit MK, Burke J, Gustafson AB, Minocha A, Peiris AN: Drug-induced disorders of glucose tolerance. Ann Int Med 118:529540, 1993


 

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David F. McAuley, Pharm.D., R.Ph.  GlobalRPh Inc.
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