logo

Gabapentin - Neurontin ® - Renal Dosing

Usual Dosing (Adults)

Usual initial dose: 300mg q8h. Usual maintenance dose: 300-600mg q8h. Maximum dosage/day: 3600 mg

Renal Dosing

dialysis [>60 ml/min]: Give usual dosage

[30-59]: Dosage range: 400-1400mg/day 
             (divided doses - Usually bid)

[15-29]: Dosage range: 200-700mg/day.

[<15]: 100-300 mg/day. Use lower end of this range for CRCL <7.5 ml/min.

Hemodialysis

dialysis Hemodialysis:
[<15 ml/min]: 100-300 mg/day. Give supplemental dose of 125-350mg after each dialysis. Dosage given should be proportional to maintenance dose. Patients receiving at least 300mg/day can be given the higher supplemental dose of 350mg after each dialysis. Other patients should receive a dosage at the lower end of this range.

Reference(s)

National Institutes of Health, U.S. National Library of Medicine, DailyMed Database.
Provides access to the latest drug monographs submitted to the Food and Drug Administration (FDA). Please review the latest applicable package insert for additional information and possible updates.  A local search option of this data can be found here.

Disclaimer

The authors make no claims of the accuracy of the information contained herein; and these suggested doses are not a substitute for clinical judgment. Neither GlobalRPh Inc. nor any other party involved in the preparation of this program shall be liable for any special, consequential, or exemplary damages resulting in whole or part from any user's use of or reliance upon this material.PLEASE READ THE DISCLAIMER CAREFULLY BEFORE ACCESSING OR USING THIS SITE. BY ACCESSING OR USING THIS SITE, YOU AGREE TO BE BOUND BY THE TERMS AND CONDITIONS SET FORTH IN THE DISCLAIMER.   Read the disclaimer
Medical Calculators - A thru Z
Lab Values - A thru Z