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NATPARA ®(PARATHYROID HORMONE)-  injection

Please see package insert for additional information and possible updates. The authors make no claims of the accuracy of the information contained herein; and these suggested doses are not a substitute for clinical judgment. Neither GlobalRPh Inc. nor any other party involved in the preparation of this program shall be liable for any special, consequential, or exemplary damages resulting in whole or part from any user's use of or reliance upon this material. PLEASE READ THE DISCLAIMER CAREFULLY BEFORE ACCESSING OR USING THIS SITE. BY ACCESSING OR USING THIS SITE, YOU AGREE TO BE BOUND BY THE TERMS AND CONDITIONS SET FORTH IN THE DISCLAIMER.    [  Read the disclaimer    |   <<Back      |  ---- led    ]
CLINICAL PHARMACOLOGY INDICATIONS AND USAGE
DOSAGE AND ADMINISTRATION HOW SUPPLIED

CLINICAL PHARMACOLOGY: top of page

Initial U.S. Approval:  2015

Mechanism of Action: NATPARA is a parathyroid hormone. Parathyroid hormone raises serum calcium by increasing renal tubular calcium reabsorption, increasing intestinal calcium absorption (i.e., by converting 25 OH vitamin D to 1,25 OH2 vitamin D) and by increasing bone turnover which releases calcium into the circulation.

INDICATIONS AND USAGE  top of page


INDICATIONS AND USAGE:
NATPARA is a parathyroid hormone indicated as an adjunct to calcium and vitamin D to control hypocalcemia in patients with hypoparathyroidism.

Limitations of Use:
Because of the potential risk of osteosarcoma, NATPARA is recommended only for patients who cannot be well-controlled on calcium supplements and active forms of vitamin D alone. [see Warnings and Precautions (5.1)]
NATPARA was not studied in patients with hypoparathyroidism caused by calcium-sensing receptor mutations.
NATPARA was not studied in patients with acute post-surgical hypoparathyroidism.

DOSAGE AND ADMINISTRATION  top of page

Drug UPDATES:  NATPARA ®(PARATHYROID HORMONE)- parathyroid hormone injection
[Drug information  /  PDF]    Click link for the latest monograph
Dosing:  Click (+) next to Dosage and Administration section (drug info link)

HOW SUPPLIED top of page

HOW SUPPLIED: NATPARA is supplied as a multiple dose, dual-chamber glass cartridge containing a sterile powder and diluent in 4 dosage strengths. [25, 50, 75, 100 mcg]

REFERENCE

Drug UPDATES:  NATPARA ®(PARATHYROID HORMONE)- parathyroid hormone injection
[Drug information  /  PDF]    Click link for the latest monograph
Dosing:  Click (+) next to Dosage and Administration section (drug info link)
Medical Calculators - A thru Z
Lab Values - A thru Z