Droperidol  Inapsine ®

Usual Diluents

D5W,   NS

Standard Dilutions   [Amount of drug]  [Infusion volume]  [Infusion rate]

[1 to 3 mg/ 50 ml] [30 min] [4 to 10 mg/ 100 ml] [As directed] ------Continuous infusion------ [25 mg/ 500 ml] [As directed]

Stability / Miscellaneous

Label: Do not Refrigerate.   Actions:  Marked sedation/ antiemetic. Premedication: 2.5 to 10mg IV / IM. Usually 1.25 to 2.5 mg q3-6h prn.  Continuous infusion: 25 mg/500 ml D5W at 1 mg/hr initially for tx of hyperemesis gravidarum (give 1 to 2.5 mg loading initially).  May increase by 0.25 mg at 4hr intervals if pt not responding (usual range: 1 to 1.25 mg/hr).  Also add benadryl 50mg q6h until infusion is stopped.   When pt is ready to take oral meds switch to reglan 10mg qid + hydroxyzine 50mg.