DILTIAZEM (CARDIZEM ®)

Usual Diluents

D5W,  NS

Standard Dilutions   [Amount of drug]  [Infusion volume]  [Infusion rate]

---Final Concentration 1 mg/ml --- [125 mg (25 ml)/ 100 ml] [Titrate]   [Total volume = 125 ml]

Stability / Miscellaneous

EXP: 1 DAY (RT) Label: Refrigerate/ concentration= 1 mg/ ml.    Dosing (A-fib/flutter) initially  0.25 mg/kg over 2 min. If inadequate give 0.35 mg/kg over 2 min-15 min after 1st dose. Subsequent doses should be individualized. Continuous infusion: started immediately following an effective bolus dose. Initial rate= 10 mg/hr (some may respond to 5 mg/hr). If needed, may increase up to 15 mg/hr. Contraindicated: AMI, hypotension (sys<90), 2nd & 3rd degree AV block.