Cidofovir - Vistide Ž - Renal Dosing

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Cidofovir
Vistide Ž

Usual Dosing (Adults)

Treatment of cytomegalovirus (CMV) retinitis: (Patient must meet the following criteria first: serum creatinine </= 1.5, CRCL >55ml/min and urine protein < 100 mg/dL). Induction: 5 mg/kg qweek x 2. Maintenance: 5 mg/kg q2weeks.
Note: Probenecid must be administered orally with each dose of cidofovir.

Renal Dosing

Cidofovir is contraindicated in patients with a serum creatinine concentration > 1.5 mg/dL, a calculated creatinine clearance </= 55 mL/min, or a urine protein >/= 100 mg/dL (equivalent to >/= 2 + proteinuria).

Hemodialysis

Contraindicated.