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Chlorpromazine
Thorazine ®
Usual Diluents
NS,  D5W 
Standard Dilutions   [Amount of drug]  [Infusion volume]  [Infusion rate]
[25 mg/ 100 ml] [30 min]
[50 mg/ 100 ml] [50-60 min]
Stability / Miscellaneous
EXP: 1 DAY (RT).  Label: Do not refrigerate// Monitor BP closely.   

The IV route is very irritating and should be reserved for severe cases only (intractable hiccups-- oral or IM dosing were not effective). 

Intractable hiccups: (1) 25 to 50 mg po tid -qid. (2) 25-50mg IM if hiccups persist for 2-3 days (3) Last choice: slow IV infusion: 25- 50mg/500- 1000 ml NS. 

If irritation at the IM injection site is a problem use the dilution listed at the beginning. IV therapy should be reserved for recumbent patients because of the potential for severe hypotension.
 


 

 

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