CEFAZOLIN (ANCEF ®)

Usual Diluents

D5W,  NS

Standard Dilutions   [Amount of drug]  [Infusion volume]  [Infusion rate]

[0 to 1 gram/ 50 ml] [30 min] [ Over 1 gram/ 100 ml] [30 min]

Stability / Miscellaneous

EXP: 24 hours (RT)/   10 Days (REF).   Label: Refrigerate.    Maximum dose/day=12 grams.  IM injection: 500mg/ 2 ml;   1 gram/ 2.5 ml H20/BS-H20.  Usual dosage: 500mg to 1g ivpb 8h. Severe: 1.5g ivpb q6h. Life threatening: 6-12g/day.   Renal dosing: >55/q6-8h || 35-54/q8h || 11-34/ 50% usual dose q12h || <10 ml/min/ 50% to full dose q24-48h. || Hemodialysis: 0.5-1g after dialysis

CEFEPIME HCL (MAXIPIME ®)

Usual Diluents

D5W,  NS

Standard Dilutions   [Amount of drug]  [Infusion volume]  [Infusion rate]

[0 to 2 grams/ 50 ml] [30 min]

Stability / Miscellaneous

EXP: 24 hr (RT)/ 7 Days (REF).  Label: Refrigerate.   IM Injection: 500mg vial/ 1.3 ml; 1 gram vial/ 2.4 ml (Sterile H2O; BS-SW; Lidocaine 0.5 to 1%; Normal saline).  Mild to moderate infection: 500mg to 2g ivpb q12h.  Severe: 2g ivpb q8h.   Renal Dosing: >60/ 0.5-2g q12h || 30-60/ 0.5g-2g q24h || 11-29/ 0.5g-1g q24h || <10/ 250-500mg q24h or 0.5-2g q48h. || HD: 1g AD || PD: 1-2g q48h

CEFOPERAZONE (CEFOBID ®)

Usual Diluents

D5W,  NS

Standard Dilutions   [Amount of drug]  [Infusion volume]  [Infusion rate]

[0 to 1 gram/ 50 ml] [30 min] [ Over 1 gram/ 100 ml] [30 min]

Stability / Miscellaneous

EXP: 1 Day (RT)/ 5 days (REF). Label: Refrigerate  Maximum daily dose: 12 grams or 4 grams for patients with advanced liver cirrhosis.

CEFOTAXIME (CLAFORAN ®)

Usual Diluents

D5W,  NS

Standard Dilutions   [Amount of drug]  [Infusion volume]  [Infusion rate]

[0 to 2 grams/ 50 ml] [30 min]

Stability / Miscellaneous

EXP: 1 day (RT / 5 days (REF).  Label: Refrigerate.   Mild infection: 1-2g ivpb q12h.  Moderate: 1-2g ivpb q8h;   Severe: 2g ivpb q6-8h;  Life threatening: 2g ivpb q4h (Max dose/day= 12g).   Renal dosing: >50/ Usual dose || 10-50/ q8-12h || <10/ q24h || HD: 0.5 to 2g ivpb q24h AD. || PD: 1g ivpb q24h.

CEFOTETAN (CEFOTAN ®)

Usual Diluents

D5W,  NS

Standard Dilutions   [Amount of drug]  [Infusion volume]  [Infusion rate]

[0 to 1 gram/ 50 ml] [30 min] [ Over 1 gram/ 100 ml] [30 min]

Stability / Miscellaneous

EXP: 1 DAY (RT);   4 DAYS (REF). Label: Refrigerate.     Maximum dose: 3 grams ivpb q12h.  Do not exceed q12h interval.     IM injection: 1 gram/ 2 ml; 2 grams/ 3 ml SW /BS-SW /NS /0.5 to 1% lidocaine.  Usual dose: 1g ivpb q12h. Severe: 2-3g ivpb q12h. (Max 6g/day).   Renal dosing: >30/ Usual dose || 10-30/ 50% of dose q12h || <10/ 25% of dose q12h.|| Hemodialysis or PD: 50% of usual dose q24h

CEFOXITIN (MEFOXIN ®)

Usual Diluents

D5W,  NS

Standard Dilutions   [Amount of drug]  [Infusion volume]  [Infusion rate]

[0 to 1 gram/ 50 ml] [30 min] [ Over 1 gram/ 100 ml] [30 min]

Stability / Miscellaneous

EXP: 1 Day (RT)/ 7 Days (REF). Label: Refrigerate.    IM injection: 1 gram/ 2ml ; 2 grams/ 4 ml. (Sterile water or lidocaine 0.5-1%).  Usual dose 1g q6-8h. Moderate-severe: 2g q6-8h. Severe: 2g q4h.   Renal dosing: 10-50/ q8-12h || <10/ q24-48h || HD: give 1g after Dialysis: e.g. Give Cefoxitin 1 gram ivpb M-W-F after dialysis + a supplemental dose on Sunday.

CEFTAZIDIME (FORTAZ ®)

Usual Diluents

D5W,  NS

Standard Dilutions   [Amount of drug]  [Infusion volume]  [Infusion rate]

[0 to 1 gram/ 50 ml] [30 min] [ Over 1 gram/ 100 ml] [30 min]

Stability / Miscellaneous

EXP: 1 DAY (RT) ;  7 DAYS (REF) Label: Refrigerate.   Maximum dose: 2 grams ivpb q8h.     IM injection: 500mg/ 1.5 ml;   1 gram/ 3 ml SW / BS-SW  / 0.5-1% lidocaine. (Intragluteal or lateral aspect of thigh).  Usual dose: 1g ivpb q8-12h. Severe: 2g ivpb q8-12h. (Max dose/day= 6 grams).   Renal dosing: Crcl 30-50/ q12h   ||  10-30/ q24h  || <10/ q48h

CEFTRIAXONE (ROCEPHIN ®)

Usual Diluents

D5W,  NS

Standard Dilutions   [Amount of drug]  [Infusion volume]  [Infusion rate]

[0 to 1 gram/ 50 ml] [30 min] [ Over 1 gram/ 100 ml] [30 min]

Stability / Miscellaneous

EXP: 1 DAY (RT) / 10 DAYS (REF).  Label: Refrigerate.   Total daily dose should not exceed 4 grams.   IM injection preparation:   250 mg/ 0.9 ml;  500mg/ 1.8 ml;  1 gram/3.6 ml;  2grams/ 4.2 or 7.2 ml  (H20;  BS-H20;   0.5 to 1% lidocaine) Usual dose: 1-2g ivpb q24h. Severe: 2g ivpb q12h.   No dosage adjustments req'd in renal failure.  PD: 750mg ivpb q12h

CEFUROXIME (ZINACEF ®)

Usual Diluents

D5W,  NS

Standard Dilutions   [Amount of drug]  [Infusion volume]  [Infusion rate]

[0 to 750 mg/ 50 ml] [30 min] [Over 750 mg/ 100 ml] [60 min]

Stability / Miscellaneous

EXP: 1 DAY (RT) ;   7 DAYS (REF).  Label: Refrigerate.    IM injection: 750 mg vial/ 3ml SW.   Usual: 750mg to 1.5g ivpb q8h. Severe: 1.5g ivpb q6-8h.   Renal Dosing: >20/q8h || 10-20/ q12h || <10/ 750mg q24h. || Hemodialysis: Give single dose after dialysis or give 750mg q12h. || PD: 750mg-1.5g q24h.