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Cefuroxime
Zinacef ®  (IV)

Cefuroxime axetil
Ceftin ®  (oral)
Usual Dosing (Adults)

IV:  750 mg to 1.5 gm IV q8h.
Oral:  250 – 500mg q12h. 

Renal Dosing
Oral:
[CRCL >10 ml/min]: no changes

[<10 ml/min]: give 250mg q24h. 
IV:
[CRCL >20 ml/min]: no changes
(750 mg to 1.5 gm IV q8h)

[10-20 ]: 750 mg q12h. 

[<10 ml/min]: 750 mg q24h.
Hemodialysis
IV:  Hemodialysis:  750mg q24h. Repeat the dose at the end of dialysis. PD: 750 mg q24h.

Oral:  Give 250 mg q24h. Repeat the dose after dialysis.


 

 

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