mild skin and skin-structure infections
gram IV or IM
Serious gynecologic and
2 grams IV
2 grams IV
life-threatening infections, especially in immunocompromised
2 grams IV
Lung infections caused by
Pseudomonas spp. in patients with cystic fibrosis with normal renal
mg/kg IV to a maximum of 6 grams per day
Neonates (0-4 weeks)
30 mg/kg IV
Infants and children
(1 month-12 years)
30-50 mg/kg IV to a maximum of 6 grams per
* Although clinical improvement has been shown, bacteriologic cures cannot be
expected in patients with chronic respiratory disease and cystic fibrosis.
†The higher dose should be reserved for immunocompromised pediatric patients or
pediatric patients with cystic fibrosis or meningitis.
[CRCL >50 ]: No changes.
[31-50 ]: 1 gram q12h.
[16-30 ]: 1 gram q24h.
[6-15 ]: 500 mg q24h.
[<5 –dialysis]: 500 mg q48h.
Note: all dosages listed for renal insufficiency may be increased by 50%
in severe infections.
Loading dose: 1 gram x 1, then 1 gram after each hemodialysis session.
[Alternatively]: Give 1 gram q48h, plus give an additional 1 gram dose
after each dialysis session.
CAPD: 1 gram x 1, followed by 500mg q24h.
National Institutes of Health, U.S. National Library of Medicine,
DailyMed Database. Provides access to the latest drug monographs submitted to the
Food and Drug Administration (FDA). Please review the latest applicable package insert for
additional information and possible updates. A local search
option of this data can be found here.
The authors make no claims of the accuracy of the information contained herein; and these suggested doses are not a substitute for clinical
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