Cefepime - Maxipime ® - Renal Dosing

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Cefepime
Maxipime ®

Usual Dosing (Adults)

[Mild to moderate]: 500 mg to 1 gram IV q12h.
[Moderate to severe]: 1-2 grams IV q12h.
[Febrile neutropenic patients]: 2 grams IV q8h.

Renal Dosing

[CRCL >60 ml/min]: no change.

[30-60 ]: 500mg to 2 grams q24h.
Neutropenic: 2 grams q12h.

[11-29 ]: 500 mg to 1 gram q24h. Neutropenic: 2 grams q24h.

[<11 ]: 250 – 500 mg q24h. Neutropenic: 1 gram q24h.

Hemodialysis

Hemodialysis:
250 – 500 mg q24h. Neutropenic: 1 gram q24h. // Give additional dose post dialysis.

PD: 1-2 grams q48h