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Cefazolin
Ancef ®
Usual
Dosing (Adults)
[Usual]: 500mg to 1g IV q8h.
[Moderate to severe]: 500mg – 1 gram q6-8h.
[life-threatening]: 1–1.5g q6h.
[Maximum dosage/day]: 12 grams.
Renal
Dosing
[CRCL >55 ml/min]: no change.
[35-54 ml/min]: Maximum interval: q8h. 500mg – 1.5g q8h.
[11-34 ml/min]: 500mg – 1.5g x 1, then 0.5 - 1 gram q12h.
[<10 ml/min]: 500 mg - 1 gram q18-24h.
Hemodialysis
500 mg – 1 gram IV q24h. (Give dose post-dialysis on dialysis days.)
