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BACTRIM ®
(trimethoprim /sulfamethoxazole)
Usual Diluents
D5W
Standard Dilutions   [Amount of drug]  [Infusion volume]  [Infusion rate]
[0 to 80 mg/ 100 ml] [60 min]
[81 to 120 mg/ 150-250 ml] [90 min]
[121 to 240 mg/ 250 ml] [90 min]
[241 to 450 mg/ 500 ml][2 hours]
Stability / Miscellaneous
EXP: 6 hours (RT) / 2hours (minimum dilution) Label: Do not Refrigerate Minimum dilution: 80 mg TMP/ 75 ml.
Non-PCP: 10mg/kg/day ( based on TMP component) divided q6h or q8h or q12h
PCP: 15-20mg/kg/day (based on TMP component) divided q6h

Renal dosing:
Non-PCP:
30: no change
15-30: 5 mg/kg/day q12h
<15: 2.5mg/kg q24h (Avoid if possible due to risk of crystalluria/ nephrolithiasis)

PCP:
50: no change
15-30: 5mg/kg q12h
<15: 5mg/kg q24h (Avoid if possible due to risk of crystalluria/ nephrolithiasis)

 

 


 

 

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