Atracurium Tracrium ®

Usual Diluents

D5W,  NS

Standard Dilutions   [Amount of drug]  [Infusion volume]  [Infusion rate]

[100 mg/ 100 ml] [Titrate] [250 mg/ 100 ml] [Titrate] [1000 mg/ 250 ml] [Titrate] (Usual concentration: 0.2 to 5 mg/ ml)

Stability / Miscellaneous

EXP: 24 hours (RT/REF).   May be given undiluted by IV bolus.  Dosing (adult): initially 0.4 to 0.5 mg/kg IV bolus, followed by  0.08 to 0.1 mg/kg q20-45 min after initial dose. Continuous infusion: initially  0.4 to 0.5 mg IV bolus, followed by 9 to 10 mcg/kg/min initially. Maintenance infusion rates of 5 to 9 mcg/kg/min are usually adequate. (Range: 2 to 15 mcg/kg/min).  Toxic metabolite (laudanosine) may accumulate in renal failure.  [Supplied: 50 mg/5 ml ; 100 mg/10ml vial]