Antihistamines

Low or non-sedating antihistamines:

cetirizine (Zyrtec):

Metabolite of hydroxyzine. Usual dose: 5-10 mg orally once daily.

desloratadine (Clarinex)

Adults: Allergic rhinitis, seasonal/perennial: 5 mg po qd.
Chronic idiopathic urticaria: 5 mg po qd. In patients with liver or renal impairment, a starting dose of one 5 mg tablet every other day is recommended based on pharmacokinetic data.

fexofenadine (Allegra):

Adult (usual) Chronic idiopathic urticaria: 60 mg orally twice daily.
Seasonal allergic rhinitis: 60 mg orally twice daily or 180 mg once daily. A dose of 60 mg once daily is recommended as the starting dose in patients with decreased renal function

loratadine (Claritin):

Adult (usual):  10 mg orally once daily.

Combination decongestant/antihistamine (Formulary)

Actifed (triprolidine 2.5mg + psuedoephedrine 60mg):

Dosing: 1 tablet orally every 4 to 6 hours as needed. Maximum of 4 tablets/day.

Allegra D

(pseudoephedrine 120mg + fexofenadine 60mg).
 Dosing: one tablet twice daily for adults and children 12 years of age and older (should be taken on an empty stomach). A dose of one tablet once daily is recommended as the starting dose in patients with decreased renal function.

Claritin-D

Claritin-D 24 hour (10mg loratadine + 240mg psuedophedrine)
Dosing (Adult): one tablet po qd.
Claritin-D 24 Hour Extended Release Tablets should generally be avoided in patients with hepatic insufficiency. Patients with renal insufficiency (GFR <30 mL/min) should be given a lower initial dose (one tablet every other day) because they have reduced clearance of loratadine and pseudoephedrine. Patients who have a history of difficulty in swallowing tablets or who have known upper gastrointestinal narrowing or abnormal esophageal peristalsis should not use this product.

Other antihistamines (Sedating)

chlorpheniramine (Chlor-Trimeton)

Adult (usual): 4 mg po every 4 to 6 hrs; maximum dose: 24 mg/day. Sustained-release: 8 or 12 mg po every 8 to 12 hours. Maximum dose: 24 mg/day.
Supplied:
Extended Release Cap: 6 mg, 8 mg, 12 mg
Liquid/syrup: 2 mg/5 ml
Tablet: 2 mg, 4 mg. Chewable: 2 mg
Extended Release tab: 8 mg, 12 mg, 16 mg

clemastine (Tavist)

Tavist 12 Hour Allergy Tablets: Clemastine fumarate, USP 1.34 mg (equivalent to 1 mg clemastine). Adults and children 12 years of age and older: take 1 tablet every 12 hours, not more than 2 tablets in 24 hours unless directed by a doctor.

cyproheptadine (Periactin):

Adult (usual): Start 4 mg orally three times a day. Maximum: 32 mg/day.

dimenhydrinate (Dramamine):

Adult (usual):  50 to 100mg orally every 4 to 6 hours as needed.
[Supplied: 25, 50mg]

diphenhydramine (Benadryl):

Adult (usual):  25-50mg oral, IV or IM every 4 to 6 hours as needed.

hydroxzine  (Atarax, Vistaril):

Adult (usual):
Antiemetic: I.M.: 25-100 mg/dose every 4-6 hours as needed.
Anxiety: Oral: 25-100 mg 4 times/day; maximum: 600 mg/day.
Preoperative sedation:  Oral: 50-100 mg. I.M.: 25-100 mg.
Management of pruritus: Oral: 25 mg 3-4 times/day

promethazine  (Phenergan)

Adult (usual) Allergy: 25 mg orally at bedtime or 12.5 mg orally before meals and at bedtime. Allergy: 25 mg IV or IM, may repeat within 2 hrs if needed. Anesthesia adjunct: 25-50 mg IM or IV prior to surgery. Motion sickness: 25 mg orally twice daily. Nausea and vomiting: 12.5-25 mg orally ,rectally, IV or IM every 4 to 6 hrs. Sedation: 25-50 mg orally or 50 mg rectally.

Administration: maximum rate of IV administration: 25 mg/min. maximum concentration for IV administration: 25 mg/mL. Administer I.M. into deep muscle (preferred route of administration). I.V. administration is NOT the preferred route.
[Supplied: 25, 50 mg/ml Injection. 12.5, 25, 50mg suppository. 10 mg/5 ml Syrup. 10, 25 , 50mg Tablet]
 

Disclaimer

Listed dosages are for - Adult patients ONLY. PLEASE READ THE DISCLAIMER CAREFULLY BEFORE ACCESSING OR USING THIS SITE. BY ACCESSING OR USING THIS SITE, YOU AGREE TO BE BOUND BY THE TERMS AND CONDITIONS SET FORTH IN THE DISCLAIMER. GlobalRPH does not directly or indirectly practice medicine or provide medical services and therefore assumes no liability whatsoever of any kind for the information and data accessed through the Service or for any diagnosis or treatment made in reliance thereon.

David F. McAuley, Pharm.D., R.Ph.  GlobalRPh Inc.