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Infection
Wound infections  Possible therapeutic alternatives
Wound: Infected, post-op or trauma, without sepsis. (Not Gastrointestinal tract or female genital tract.) Common pathogens
Cephalexin 500mg orally 4 times daily or 
Duricef 1 gram orally once daily or cin 500mg po q12h or
Augmentin 500mg orally three times daily   or 
Dicloxacillin 500mg orally 4 times daily +/- Ciprofloxacin
Wound infection + sepsis. (does not include surgery involving GI or female genital tract) Common pathogens
Ampicillin-sulbactam 1.5 - 3 grams IV every 6 hours  or
Ticarcillin-clavulanic acid  3.1 grams  IV every 6 hours or  
Piperacillin-tazobactam 3.375 grams IV every 6 hours or 
Cefazolin 1 gram  IV every 8 hours.
Postop wound (surgery involving gastrointestinal tract or female genital tract)  (all regimens must cover anaerobes) Common pathogens
Cefotetan 2 grams ivpb q12h or   or 
Cefoxitin 1 gram IV every 6 hours or
Ticarcillin-clavulanic acid  3.1grams IV every 6 hours  or 
Ampicillin-sulbactam 1.5-3g ivpb q6h or  
[ (Cefotaxime 1g ivpb q8h or Ceftriaxone1-2g ivpb q24h ) +  Metronidazole 500mg ivpb q6-8h]  or
Imipenem 500mg ivpb q6h.

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References - Infectious Disease Section
Infectious Disease References

Disclaimer
The authors make no claims of the accuracy of the information contained herein; and these suggested doses are not a substitute for clinical judgement. Neither GlobalRPh Inc. nor any other party involved in the preparation of this program shall be liable for any special, consequential, or exemplary damages resulting in whole or part from any user's use of or reliance upon this material.
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