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Pyelonephritis

Pyelonephritis
Duration of therapy: Usually for 14 days.  If recurrent or failure after 14 days, treat for 6 weeks.
Possible therapeutic alternatives

 

Uncomplicated
(Outpatient treatment).


Therapy length:
14 days
Common pathogens
Ciprofloxacin 500mg orally twice daily OR.    
Norfloxacin 400mg orally twice daily OR
Ofloxacin 200- 400mg orally twice daily OR
Levofloxacin 750mg orally once daily for 14 days OR
Augmentin  875/125 mg orally twice daily or  500/125mg three times daily
Hospitalized patient (recommend IV therapy until afebrile. Usually 24-48h, then switch to oral therapy Common pathogens
Ciprofloxacin 200 to 400mg IV every 12 hours  OR
Levofloxacin 500mg IV once daily OR
[Ampicillin 1-2 gram IV every 6 hours + gentamicin IV]   OR
Ceftriaxone 2 grams IV once daily for 14 days OR
Ampicillin-sulbactam 1.5 to 3 grams IV every 6 hours
OR
Piperacillin-tazobactam 3.375 grams IV q6h for 14 days.

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References - Infectious Disease Section

Infectious Disease References

Disclaimer

The authors make no claims of the accuracy of the information contained herein; and these suggested doses are not a substitute for clinical judgement. Neither GlobalRPh Inc. nor any other party involved in the preparation of this program shall be liable for any special, consequential, or exemplary damages resulting in whole or part from any user's use of or reliance upon this material.
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