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Pyelonephritis

Pyelonephritis
Duration of therapy: Usually for 14 days.  If recurrent or failure after 14 days, treat for 6 weeks.
Possible therapeutic alternatives

 

Uncomplicated
(Outpatient treatment).

Therapy length:
14 days

Common pathogens
Ciprofloxacin 500mg orally twice daily OR.    
Norfloxacin 400mg orally twice daily OR
Ofloxacin 200- 400mg orally twice daily OR
Levofloxacin 750mg orally once daily for 14 days OR
Augmentin  875/125 mg orally twice daily or  500/125mg three times daily
Hospitalized patient (recommend IV therapy until afebrile. Usually 24-48h, then switch to oral therapy Common pathogens
Ciprofloxacin 200 to 400mg IV every 12 hours  OR
Levofloxacin 500mg IV once daily OR
[Ampicillin 1-2 gram IV every 6 hours + gentamicin IV]   OR
Ceftriaxone 2 grams IV once daily for 14 days OR
Ampicillin-sulbactam 1.5 to 3 grams IV every 6 hours
OR
Piperacillin-tazobactam 3.375 grams IV q6h for 14 days.

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pyelone
Pyelonephritis