Anti-tussives / Expectorants (Products for cough)

Anti-tussives / Expectorants:

Benzonatate ( Tessalon ®)	guaifenesin ( Robitussin ®)
Robitussin AC ®	Robitussin DM ®
Robitussin CF ®	Robitussin PE ®

Benzonatate ( Tessalon ®)

CLINICAL PHARMACOLOGY
Benzonatate acts peripherally by anesthetizing the stretch receptors located in the respiratory passages, lungs, and pleura by dampening their activity and thereby reducing the cough reflex at its source. It begins to act within 15 to 20 minutes and its effect lasts for 3 to 8 hours. Benzonatate capsules have no inhibitory effect on the respiratory center in recommended dosage.

INDICATIONS AND USAGE
Benzonatate capsules are indicated for the symptomatic relief of cough.

CONTRAINDICATIONS
Hypersensitivity to benzonatate or related compounds.

WARNINGS
Severe hypersensitivity reactions (including bronchospasm, laryngospasm and cardiovascular collapse) have been reported which are possibly related to local anesthesia from sucking or chewing the capsule instead of swallowing it. Severe reactions have required intervention with vasopressor agents and supportive measures.

Isolated instances of bizarre behavior, including mental confusion and visual hallucinations, have also been reported in patients taking benzonatate capsules in combination with other prescribed drugs.

Dosage
Children >10 years and Adults: Oral: 100 mg 3 times/day or every 4 hours up to 600 mg/day

Supplied
Capsule: 100 mg
Tessalon®: 100 mg, 200 mg

guaifenesin ( Robitussin ®)

Use: helps loosen phlegm (mucus) and thin bronchial secretions to rid the bronchial passageways of bothersome mucus and make coughs more productive

Children >12 years and Adults:
Suspension: (guaifenesin 100 mg/5 ml): 200-400 mg (2 to 4 teaspoonfuls) orally every 4 hours as needed. Maximum of 24 teaspoonfuls per day.

Humabid LA (600mg tabs): 1-2 tabs every 12 hours. Maximum 4 tabs/day.

Regular release- (200 mg tabs): Adults and children 12 years of age and older: One to 2 tablets (200 mg to 400 mg) every four hours, not to exceed 2400 mg (12 tablets) in 24 hours.

Robitussin AC ®

Adults and children 12 years of age and over: 2 teaspoonfuls every 4 hours, not to exceed 12 teaspoonfuls in a 24-hour period.

Children 6 to under 12 years: 1 teaspoonful every 4 hours, not to exceed 6 teaspoonfuls in a 24-hour period.

Supplied: Each teaspoonful (5 ml) contains: Guaifenesin 100 mg, Codeine Phosphate 10 mg.

Robitussin DM ®

Adults and children 12 years and over: 2 teaspoonfuls orally every 4 hours, up to a maximum of 6 doses each 24 hours. (Maximum 12 teaspoonfuls /day).

Supplied: Each teaspoonful (5 ml) contains: Guaifenesin 100 mg, Dextromethorphan Hydrobromide 10 mg.

Robitussin CF ®

Adult dose: 2 teaspoonfuls every 4 hrs. Do not take more than 4 doses in any 24 hour period.

Supplied: Each teaspoonful (5 ml) contains: Guaifenesin 100 mg, Pseudoephedrine hcl 30 mg, Dextromethorphan Hydrobromide 10 mg.

Robitussin PE ®

Adult dose (and children 12 years and over): 2 teaspoonfuls every 4 hrs. Do Not Exceed 4 Doses in any 24-Hour Period.

Supplied: Each teaspoonful (5 ml) contains: Guaifenesin 100 mg, Pseudoephedrine HCl 30 mg.

Disclaimer

Listed dosages are for - Adult patients ONLY. PLEASE READ THE DISCLAIMER CAREFULLY BEFORE ACCESSING OR USING THIS SITE. BY ACCESSING OR USING THIS SITE, YOU AGREE TO BE BOUND BY THE TERMS AND CONDITIONS SET FORTH IN THE DISCLAIMER. GlobalRPH does not directly or indirectly practice medicine or provide medical services and therefore assumes no liability whatsoever of any kind for the information and data accessed through the Service or for any diagnosis or treatment made in reliance thereon.

David F. McAuley, Pharm.D., R.Ph. GlobalRPh Inc.