Acne Treatments

adapalene  (Differin ®)

 Topical retinoid-like compound. Acne vulgaris (adult): after washing, apply a thin film topically to affected area(s) once daily at bedtime.
[Supplied 0.1% cream/solution/gel]

azelaic acid  (Azelex ®)

 Adult (usual) Mild-to-moderate inflammatory acne: apply a thin film topically to affected area twice daily. Indications: topical treatment of vulgaris. Azelaic acid is a naturally-occurring, saturated, straight-chained dicarboxylic acid.
[Supplied 20% cream]

BenzaClin ®

Topical Gel. Apply twice daily, morning and evening, or as directed by a physician, to affected areas after the skin is gently washed, rinsed with warm water and patted dry.
[Supplied: Each gram of BenzaClin Topical Gel contains, 10 mg (1%) clindamycin as phosphate and 50 mg (5%) benzoyl peroxide]

Benzamycin ®

Topical Gel. Apply twice daily, morning and evening, or as directed by a physician to affected areas after the skin is thoroughly washed, rinsed with warm water and gently patted dry.
[Supplied: Topical gel - erythromycin 3%-benzoyl peroxide 5% ]

Benzoyl Peroxide

Adult (usual) Acne: apply 2.5%-10% concentration topically once or twice daily. Benzoyl peroxide is an antibacterial, mildly comedolytic, and sebostatic agent.
[Supplied: several dosage forms - gels, creams, suspensions, ...]

clindamycin (Cleocin ®)

Acne vulgaris: apply thin film of solution, lotion, or gel topically twice daily to affected areas [Supplied: 1% gel/lotion/solution]

Duac ®

 Topical Gel. Apply once daily in the evening or as directed by the physician, to affected areas after the skin is gently washed, rinsed with warm water and patted dry.
[Supplied: 1% clindamycin, and 5% benzoyl peroxide topical gel]

Erythromycin

ERYGEL® 2% Topical Gel should be applied sparingly as a thin film to affected area(s) once or twice a day after the skin is thoroughly cleansed and patted dry. If there has been no improvement after 6 to 8 weeks, or if the condition becomes worse, treatment should be discontinued, and the physician should be reconsulted. Spread the medication lightly rather than rubbing it in. There are no data directly comparing the safety and efficacy of b.i.d. versus q.d. dosing.
ERYGEL® 2% topical solution: wash skin with soap and warm water and pat dry. Apply to affected area bid with a dabbing motion.

Glycolic Acid  -  (BioMedic ® Cellex-C ® Glytone ® )

Glycolic Acids have been reported to improve acne, pseudofoliculites, barbae, ichthyosis/xerosis, as well as premature aging of the skin.

Seattle Dermatologist: "Glycolic Acid has been proven to be very effective in the treatment of acne as well as the cosmetic benefits one receives. I feel that the use of glycolic acid, especially for the treatment of acne, is the most exciting development in the field of facial skin care over the past decade. It is my prediction that glycolic acid will soon become the standard treatment approach for acne."

Isotretinoin (Accutane ®)

Adult (usual) - Severe recalcitrant nodular acne: 0.5-2 mg/kg/day orally in 2 divided doses for 15-20 weeks.
[Supplied 10 mg, 20 mg, 40 mg capsule]

Sulfacetamide with sulfur  (Sulfacet-R ®)

Indications: topical control of acne is, acne rosacea and seborrheic dermatitis. Clean the affected area and apply a thin layer of medication to the skin 1 to 3 times daily; or use as directed by your doctor. (Shake Well before using.)
Expiration date after reconstituting: four months. [Supplied: sodium sulfacetamide 10% and sulfur 5% topical lotion]

Tazarotene  (Tazorac ®)

Acne vulgaris: apply 0.1% gel or cream every night to affected area .
[Supplied 0.05%, 0.1% cream. 0.05%, 0.1% gel]

Tretinoin  (Retin-A ®)

Acne vulgaris: apply 0.025%-0.1% cream or 0.05% liquid topically at bedtime.

Fine wrinkles/ mottled hyperpigmentation /tactile roughness: apply 0.025%-0.05% cream at bedtime.

Retin-A Micro (tretinoin gel) microsphere, 0.1% and 0.04% - this formulation uses patented methyl methacrylate/glycol dimethacrylate crosspolymer porous microspheres (Microsponge® System) to enable inclusion of the active ingredient, tretinoin, in an aqueous gel. Retin-A Micro should be applied once a day, in the evening, to the skin where acne lesions appear, using enough to cover the entire affected area lightly. Application of excessive amounts of gel may result in "caking" of the gel, and will not provide incremental efficacy.

Supplied: cream/gel/liquid - various concentrations.



 

Disclaimer

Listed dosages are for - Adult patients ONLY. PLEASE READ THE DISCLAIMER CAREFULLY BEFORE ACCESSING OR USING THIS SITE. BY ACCESSING OR USING THIS SITE, YOU AGREE TO BE BOUND BY THE TERMS AND CONDITIONS SET FORTH IN THE DISCLAIMER. GlobalRPH does not directly or indirectly practice medicine or provide medical services and therefore assumes no liability whatsoever of any kind for the information and data accessed through the Service or for any diagnosis or treatment made in reliance thereon.

David F. McAuley, Pharm.D., R.Ph.  GlobalRPh Inc.