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Acetylcysteine
Acetadote ®
Usual Diluents
D5W
Standard Dilutions   [Amount of drug]  [Infusion volume]  [Infusion rate]
Acetaminophen overdose:
Adult Loading dose: 
[150mg/kg] [200 ml] [15 min]

Maintenance dose:
[50 mg/kg] [500ml] [over 4 hrs]
Followed by:
[100 mg/kg] [1000ml] [over 16 hrs]

Important note: in fluid restricted patients or patients <40kg: the volume of D5W used should be reduced proportionately.
Stability / Miscellaneous
Stability: 24 hours room temp. 
Supplied: Acetadote injection is available as a 20% solution in 30 ml (200mg/ml) single glass vials. 

Do not use previously opened vials for IV administration.See package insert for additional comments.
 


 

 

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